In the past two decades, we have witnessed rapid development in the field of nanomedicine, where various nanomaterials have been synthesized or fabricated to achieve sensing, imaging, and therapeutic applications both in vitro and in vivo. Multifunctional or integrated nanomaterials have been demonstrated capable of sensing, imaging, and curing diseases on the same platform with performance superior to the conventional approaches. However, how to deliver nanomaterials to the disease sites with high efficiency is always a major challenge for researchers. Several strategies have been proposed to circumstance the hinders for nanomaterial devilry at different scales. Among them, those inspired by the biological system, such as mimicking chemical compositions on the cell membrane, have drawn a lot of attention. With various surface modification schemes, nanomaterials can be engineered with different functionality similar to native cells in the body. It is essential to design the surfaces of nanomaterials to fit specific clinical applications.
This research topic emphasizes the design principles of the bioinspired nanomaterials for sensing and therapeutic. In the optimal scenario, the designed nanomaterials work as carriers, where various functional ligands against diseases will be integrated on the same platform. The bioinspired nanomaterials should be stealthy in circulation to avoid MPS clearance, and the tissue-specific targeting moieties may be engineered on the nanomaterials to reach the disease sites. In addition, these bioinspired nanomaterials should be able to sense their surroundings to release their payloads at the suitable compartments or environments smartly. To communicate with the outside work, the positions of nanomaterials should be visualized from outside the cells or bodies. Any approaches inspired by the existing biological systems to achieve any of the above-mentioned goals are welcome in this research topic.
We welcome articles (Original Research, Review, Mini Review, and Perspective) addressing the design principle of bioinspired nanomaterials for sensing, imaging, and therapeutic. Specific themes include (but are not limited to):
• Synthesis and engineering of nanomaterials mimicking biological systems
• Bioinspired synthesis of inorganic, carbon, and supramolecular nanoparticles
• Design of multifunctional nanomaterials for sensing, imaging, and therapeutic
• Surface modifications of nanomaterials for better biocompatibility and circulation
• Surface engineering for specific targeting
• Design for smart payload releasing
• Tracking of nanomaterials in vitro and in vivo
• Imaging of the diseased tissues
In the past two decades, we have witnessed rapid development in the field of nanomedicine, where various nanomaterials have been synthesized or fabricated to achieve sensing, imaging, and therapeutic applications both in vitro and in vivo. Multifunctional or integrated nanomaterials have been demonstrated capable of sensing, imaging, and curing diseases on the same platform with performance superior to the conventional approaches. However, how to deliver nanomaterials to the disease sites with high efficiency is always a major challenge for researchers. Several strategies have been proposed to circumstance the hinders for nanomaterial devilry at different scales. Among them, those inspired by the biological system, such as mimicking chemical compositions on the cell membrane, have drawn a lot of attention. With various surface modification schemes, nanomaterials can be engineered with different functionality similar to native cells in the body. It is essential to design the surfaces of nanomaterials to fit specific clinical applications.
This research topic emphasizes the design principles of the bioinspired nanomaterials for sensing and therapeutic. In the optimal scenario, the designed nanomaterials work as carriers, where various functional ligands against diseases will be integrated on the same platform. The bioinspired nanomaterials should be stealthy in circulation to avoid MPS clearance, and the tissue-specific targeting moieties may be engineered on the nanomaterials to reach the disease sites. In addition, these bioinspired nanomaterials should be able to sense their surroundings to release their payloads at the suitable compartments or environments smartly. To communicate with the outside work, the positions of nanomaterials should be visualized from outside the cells or bodies. Any approaches inspired by the existing biological systems to achieve any of the above-mentioned goals are welcome in this research topic.
We welcome articles (Original Research, Review, Mini Review, and Perspective) addressing the design principle of bioinspired nanomaterials for sensing, imaging, and therapeutic. Specific themes include (but are not limited to):
• Synthesis and engineering of nanomaterials mimicking biological systems
• Bioinspired synthesis of inorganic, carbon, and supramolecular nanoparticles
• Design of multifunctional nanomaterials for sensing, imaging, and therapeutic
• Surface modifications of nanomaterials for better biocompatibility and circulation
• Surface engineering for specific targeting
• Design for smart payload releasing
• Tracking of nanomaterials in vitro and in vivo
• Imaging of the diseased tissues