Chronic kidney disease is a leading risk factor in the development of cardiovascular disease and is associated with greater risk of adverse cardiovascular events and mortality. Therefore, reducing the risk of cardiovascular disease in individuals with chronic kidney disease is of high priority. The identification of high-risk patients, prior to the onset of cardiovascular disease, could permit the implementation and development of new preventative therapies.
Cardiovascular Epidemiology and Prevention is devoted to reviews and studies on the distribution and determinants of cardiovascular diseases and related conditions in the population and the application of preventive strategies to reduce their occurrence. The dramatic increase in incidence of cardiovascular diseases in the past few decades in middle- and low-income countries emphasizes the urgency for further studies to understand the causes of cardiovascular disease and effective preventive strategies, including improving population screening and risk prediction.
Frontiers in Cardiovascular Medicine has organised a research topic in Cardiovascular Epidemiology and Prevention on the relationship between renal function and related biomarkers in cardiovascular risk and prevention. Renal function and biomarkers such as albuminuria, proteinuria, and uric acid have the potential to allow the identification of patients at a high-risk for the development of cardiovascular disease and could signal potential mechanistic pathways.
In patients with chronic kidney disease, numerous biomarkers have been identified via research, however their applicability for routine clinical application remains to be fully evaluated. Moreover, there is a lack of reproducibility and standardization in research in the role of such measurements in cardiovascular risk. In addition, there is limited understanding of how such measurements may vary between populations. This article collection will highlight novel epidemiological research, in different population groups in order to evaluate the correlation between cardiovascular risk and renal biomarkers.
Potential sub-topics within this theme may include, but are not limited to:
• Uremic toxins and cardiovascular risk.
• Proteomic studies of serum biomarkers for cardiovascular risk assessment.
• Renal biomarkers in the prediction of cardiovascular disease.
• Prevention of cardiovascular disease in patients with chronic kidney disease.
Cardiovascular Epidemiology and Prevention welcomes the submission of original research articles (epidemiologic, clinical or preclinical, or systematic reviews or meta-analyses), expert reviews, mini reviews, brief research articles, and case reports. Original research articles include manuscripts reporting results from epidemiologic or population studies or clinical investigations, including Phase I-III and post-marketing trials as well as from systematic reviews or meta-analyses.
Chronic kidney disease is a leading risk factor in the development of cardiovascular disease and is associated with greater risk of adverse cardiovascular events and mortality. Therefore, reducing the risk of cardiovascular disease in individuals with chronic kidney disease is of high priority. The identification of high-risk patients, prior to the onset of cardiovascular disease, could permit the implementation and development of new preventative therapies.
Cardiovascular Epidemiology and Prevention is devoted to reviews and studies on the distribution and determinants of cardiovascular diseases and related conditions in the population and the application of preventive strategies to reduce their occurrence. The dramatic increase in incidence of cardiovascular diseases in the past few decades in middle- and low-income countries emphasizes the urgency for further studies to understand the causes of cardiovascular disease and effective preventive strategies, including improving population screening and risk prediction.
Frontiers in Cardiovascular Medicine has organised a research topic in Cardiovascular Epidemiology and Prevention on the relationship between renal function and related biomarkers in cardiovascular risk and prevention. Renal function and biomarkers such as albuminuria, proteinuria, and uric acid have the potential to allow the identification of patients at a high-risk for the development of cardiovascular disease and could signal potential mechanistic pathways.
In patients with chronic kidney disease, numerous biomarkers have been identified via research, however their applicability for routine clinical application remains to be fully evaluated. Moreover, there is a lack of reproducibility and standardization in research in the role of such measurements in cardiovascular risk. In addition, there is limited understanding of how such measurements may vary between populations. This article collection will highlight novel epidemiological research, in different population groups in order to evaluate the correlation between cardiovascular risk and renal biomarkers.
Potential sub-topics within this theme may include, but are not limited to:
• Uremic toxins and cardiovascular risk.
• Proteomic studies of serum biomarkers for cardiovascular risk assessment.
• Renal biomarkers in the prediction of cardiovascular disease.
• Prevention of cardiovascular disease in patients with chronic kidney disease.
Cardiovascular Epidemiology and Prevention welcomes the submission of original research articles (epidemiologic, clinical or preclinical, or systematic reviews or meta-analyses), expert reviews, mini reviews, brief research articles, and case reports. Original research articles include manuscripts reporting results from epidemiologic or population studies or clinical investigations, including Phase I-III and post-marketing trials as well as from systematic reviews or meta-analyses.
