As of 2016, the World Health Organisation estimated 650 million adults were thought to be obese. As shocking, 17.9 million people die each year due to cardiovascular disease making it the leading cause of death globally. As a result, the far reaching implications of metabolic syndromes such as obesity and cardiovascular disease, including the heavy economic burden places on the healthcare system, highlights the importance of early detection and management. Non-alcoholic fatty liver disease (NAFLD) is a condition characterised by significant fat accumulation in the liver in the absence of excessive alcohol consumption. NAFLD is present in up to 75% of people who are overweight and in more than 90% of people who have severe obesity. Growing evidence indicates that patients with NAFLD and are at higher risk of cardiovascular disease supported by several shared pathophysiological pathways. Moreover, different studies showed that NAFLD is associated with impaired cardiac conduction, structure and function. While potential mechanisms have been suggested, the underlying relationship and the effect of novel therapies are currently not well explored and further research is needed.
This Research Topic aims to provide insight into several aspects of the connections between NAFLD cardiac conduction, structure and function, and present novelties on the potential pathological mechanism at the basis of these relationships.
Authors are welcome to submit papers on innovative findings regarding the potential linking NAFLD, cardiac conduction, structure and function. This research topic will be open to research articles [basic and applied research], meta-analyses, as well as state-of-the-art reviews and therapeutic options. Articles should cover, but are not limited to the following subjects:
• The relationship of obesity with cardiac conduction, structure and function
• The relationship between NAFLD and impaired cardiac function
• The potential pathological mechanism at the basis of these relationships
As of 2016, the World Health Organisation estimated 650 million adults were thought to be obese. As shocking, 17.9 million people die each year due to cardiovascular disease making it the leading cause of death globally. As a result, the far reaching implications of metabolic syndromes such as obesity and cardiovascular disease, including the heavy economic burden places on the healthcare system, highlights the importance of early detection and management. Non-alcoholic fatty liver disease (NAFLD) is a condition characterised by significant fat accumulation in the liver in the absence of excessive alcohol consumption. NAFLD is present in up to 75% of people who are overweight and in more than 90% of people who have severe obesity. Growing evidence indicates that patients with NAFLD and are at higher risk of cardiovascular disease supported by several shared pathophysiological pathways. Moreover, different studies showed that NAFLD is associated with impaired cardiac conduction, structure and function. While potential mechanisms have been suggested, the underlying relationship and the effect of novel therapies are currently not well explored and further research is needed.
This Research Topic aims to provide insight into several aspects of the connections between NAFLD cardiac conduction, structure and function, and present novelties on the potential pathological mechanism at the basis of these relationships.
Authors are welcome to submit papers on innovative findings regarding the potential linking NAFLD, cardiac conduction, structure and function. This research topic will be open to research articles [basic and applied research], meta-analyses, as well as state-of-the-art reviews and therapeutic options. Articles should cover, but are not limited to the following subjects:
• The relationship of obesity with cardiac conduction, structure and function
• The relationship between NAFLD and impaired cardiac function
• The potential pathological mechanism at the basis of these relationships
