Radiosurgery is an established treatment modality for a wide spectrum of lesions including benign and malignant intracranial pathologies. It can be applied as a single fraction as in stereotactic radiosurgery (SRS), or as fractionated stereotactic radiotherapy (FSRT) in which multiple fractions (2-5) are administered over a period of 2–4 weeks. It is not based on variable tissue response to fractionated radiation.
Irrespective of radiosensitivity, it provides a high control over the targeted volume, as it does not depend on the stage of a cell cycle for radiation to impart its effect. It delivers a high dose of radiation in a single/multiple session to a stereotactically defined target by converging multiple beams of ionizing radiation. The chances of collateral damage by radiation to the neighboring structures are minimized by virtue of rapid dose fall out, high precision, and conformity offered by the advanced versions of the gamma knife machine and planning software while maintaining good target control.
While microsurgery has advanced rapidly there remain areas of the brain where achieving complete resection can result in irreparable deficits and decreased quality of life. We propose radio-surgery as the 'fail-safe' for such cases to allow tumor control while preserving quality of life and preventing deficits. In addition, newer areas of application like gliomas and asymptomatic meningiomas are growing the repertoire of radiosurgery.
We call for articles and original contributions which highlight the role of radio-surgery in providing oncological control while maintaining functional superiority. Articles should be focused and accompanied with a literature review in all cases. Articles highlighting complications and their management would be given preference.
Potential research themes include, but are not limited to:
1) Oncological control of lesions in difficult to reach areas of the brain.
2) A good functional outcome despite the same.
3) Fractionation as a way to deal with larger lesions.
4) Increased areas of application of radio-surgery like recurrent and malignant gliomas.
5) Future and proposals for increased pathologies.
6) Potential complications and their management.
Radiosurgery is an established treatment modality for a wide spectrum of lesions including benign and malignant intracranial pathologies. It can be applied as a single fraction as in stereotactic radiosurgery (SRS), or as fractionated stereotactic radiotherapy (FSRT) in which multiple fractions (2-5) are administered over a period of 2–4 weeks. It is not based on variable tissue response to fractionated radiation.
Irrespective of radiosensitivity, it provides a high control over the targeted volume, as it does not depend on the stage of a cell cycle for radiation to impart its effect. It delivers a high dose of radiation in a single/multiple session to a stereotactically defined target by converging multiple beams of ionizing radiation. The chances of collateral damage by radiation to the neighboring structures are minimized by virtue of rapid dose fall out, high precision, and conformity offered by the advanced versions of the gamma knife machine and planning software while maintaining good target control.
While microsurgery has advanced rapidly there remain areas of the brain where achieving complete resection can result in irreparable deficits and decreased quality of life. We propose radio-surgery as the 'fail-safe' for such cases to allow tumor control while preserving quality of life and preventing deficits. In addition, newer areas of application like gliomas and asymptomatic meningiomas are growing the repertoire of radiosurgery.
We call for articles and original contributions which highlight the role of radio-surgery in providing oncological control while maintaining functional superiority. Articles should be focused and accompanied with a literature review in all cases. Articles highlighting complications and their management would be given preference.
Potential research themes include, but are not limited to:
1) Oncological control of lesions in difficult to reach areas of the brain.
2) A good functional outcome despite the same.
3) Fractionation as a way to deal with larger lesions.
4) Increased areas of application of radio-surgery like recurrent and malignant gliomas.
5) Future and proposals for increased pathologies.
6) Potential complications and their management.
