The eye is an important visual organ that reflects the state of the whole body such as vascular elasticity and blood lipid levels. Eye defects are involved in many endocrine disorders, which often alter both the structure and the function of the eyes. The structural alterations can be discernible under clinical examinations, but the functional changes might require many state-of-the-art imaging techniques to check. Many intrinsic errors of metabolism or endocrine syndromes have characteristic ophthalmic manifestations, which will help the ophthalmologists to facilitate the natural course of diagnosis. The awareness about the ophthalmic aberrations would also aid the endocrinologists in achieving a correct syndromic diagnosis. The common platform of ophthalmology and endocrinology should not be limited to Graves' ophthalmopathy and diabetic retinopathy (DR). More and more research has revealed that bioenergy metabolism, DNA damage repair, and hormone regulation are related to eye diseases such as age-related macular degeneration (AMD), or central serous chorioretinopathy (CSC). Metabolomics, proteomics, and other technologies are also increasingly applied to the study of eye diseases. Thus, studying ocular diseases from a system level might pave a path to dissect the relationship between eye diseases and metabolism and endocrinology.
This Research Topic aims to provide insights into the relationship between metabolism, endocrinology, and eye diseases in the respects of molecular mechanisms, pathogenic pathways, and targeted therapy. We aim to collect the up-to-date studies of eye diseases from the perspectives of proteomics, metabolomics, and genomics in the context of clinical data and relevant animal models.
Review papers and Original Research articles on the following sub-topics are welcome:
• Omics, such as proteomics, metabolomics in ophthalmic diseases.
• Clinical research on ophthalmological diseases such as CSC (central serous chorioretinopathy), AMD (age-related macular diseases), DR (diabetic retinopathy), hyperthyroidism ophthalmopathy.
• Basic research on therapeutic targets of metabolism-related ophthalmopathy.
• Studies of molecular mechanisms, e.g., DNA metabolism, glucose endocrinology, underlying clinical ocular diseases.
• Methodologies on the research of eye diseases including machine learning, imaging, animal models.
The eye is an important visual organ that reflects the state of the whole body such as vascular elasticity and blood lipid levels. Eye defects are involved in many endocrine disorders, which often alter both the structure and the function of the eyes. The structural alterations can be discernible under clinical examinations, but the functional changes might require many state-of-the-art imaging techniques to check. Many intrinsic errors of metabolism or endocrine syndromes have characteristic ophthalmic manifestations, which will help the ophthalmologists to facilitate the natural course of diagnosis. The awareness about the ophthalmic aberrations would also aid the endocrinologists in achieving a correct syndromic diagnosis. The common platform of ophthalmology and endocrinology should not be limited to Graves' ophthalmopathy and diabetic retinopathy (DR). More and more research has revealed that bioenergy metabolism, DNA damage repair, and hormone regulation are related to eye diseases such as age-related macular degeneration (AMD), or central serous chorioretinopathy (CSC). Metabolomics, proteomics, and other technologies are also increasingly applied to the study of eye diseases. Thus, studying ocular diseases from a system level might pave a path to dissect the relationship between eye diseases and metabolism and endocrinology.
This Research Topic aims to provide insights into the relationship between metabolism, endocrinology, and eye diseases in the respects of molecular mechanisms, pathogenic pathways, and targeted therapy. We aim to collect the up-to-date studies of eye diseases from the perspectives of proteomics, metabolomics, and genomics in the context of clinical data and relevant animal models.
Review papers and Original Research articles on the following sub-topics are welcome:
• Omics, such as proteomics, metabolomics in ophthalmic diseases.
• Clinical research on ophthalmological diseases such as CSC (central serous chorioretinopathy), AMD (age-related macular diseases), DR (diabetic retinopathy), hyperthyroidism ophthalmopathy.
• Basic research on therapeutic targets of metabolism-related ophthalmopathy.
• Studies of molecular mechanisms, e.g., DNA metabolism, glucose endocrinology, underlying clinical ocular diseases.
• Methodologies on the research of eye diseases including machine learning, imaging, animal models.