Skin scars arise as a result of wound healing following different pathways, such as injury, diseases (such as acne), and surgery. Pathological scars are caused by the formation of a large extracellular matrix and fibroblasts proliferation. Collagen is deposited in an uncontrolled manner during wound healing and patients with pathological scars often present other types of symptoms such as pain, itching, and erythema. As this may lead to malformations in appearance and function, pathological scars can seriously affect the well-being of an individual. For example formations of keloids and/or hypertrophic scars may seriously inhibit movements and be prone to malignant change.
As they are a source of psychological and physiological distress in humans there is a great research effort that is being invested in improving the wound healing process, reducing scar formation.
Multiple treatment strategies have been developed for the management of scars, however, there is still no uniform treatment due to a lack of comparison among the different results in clinical efficacy.
With this Research Topic, we would like to collect all the ongoing research in pathological scars, and improved wound healing strategies, which would provide novel possible treatments and favorable approaches both in safety and efficacy.
Authors are welcome to submit reviews, original research, and other article types on the recent advances in pathological scar treatments, regardless of the scar origin and on improved wound healing strategies.
Skin scars arise as a result of wound healing following different pathways, such as injury, diseases (such as acne), and surgery. Pathological scars are caused by the formation of a large extracellular matrix and fibroblasts proliferation. Collagen is deposited in an uncontrolled manner during wound healing and patients with pathological scars often present other types of symptoms such as pain, itching, and erythema. As this may lead to malformations in appearance and function, pathological scars can seriously affect the well-being of an individual. For example formations of keloids and/or hypertrophic scars may seriously inhibit movements and be prone to malignant change.
As they are a source of psychological and physiological distress in humans there is a great research effort that is being invested in improving the wound healing process, reducing scar formation.
Multiple treatment strategies have been developed for the management of scars, however, there is still no uniform treatment due to a lack of comparison among the different results in clinical efficacy.
With this Research Topic, we would like to collect all the ongoing research in pathological scars, and improved wound healing strategies, which would provide novel possible treatments and favorable approaches both in safety and efficacy.
Authors are welcome to submit reviews, original research, and other article types on the recent advances in pathological scar treatments, regardless of the scar origin and on improved wound healing strategies.
