About this Research Topic
With the publications of the International subarachnoid aneurysm trial (ISAT), endovascular treatment has become one of the most important treatments of intracranial aneurysms, and was used more and more in clinic settings. However, intracranial complex aneurysms (such as giant aneurysms, wide-necked aneurysms, fusiform aneurysms and dissecting aneurysms) still impose a huge challenge for clinicians. Flow diverter (FD) is a novel device for the treatment of aneurysms based on the understanding of hemodynamic mechanism of aneurysm occlusion. It could divert the blood flow from the aneurysm neck, and promote aneurysm occlusion without inserting coils into the aneurysms. In addition, the FDs had the advantage of simplifying the procedure and relieving the mass effect.
FDs were first used in internal carotid artery large or giant unruptured aneurysms. With the excellent efficacy of FDs in the aneurysm treatment, FDs have also been used in off-label circumstances such as posterior circulation aneurysms, distal artery aneurysms, ruptured aneurysms, and traumatic aneurysms, etc. However, while the safety and efficacy of FDs in internal carotid unruptured aneurysms have been proved, the off-label use in posterior circulation, distal arteries, ruptured aneurysms, and traumatic aneurysms, etc, is still in controversy. Some studies indicated that FDs in such aneurysms are feasible and effective, but the complications were not negligible. How to decrease the complications in such aneurysms remains a great challenge for physicians. By investigating the treatment effect of FDs in such aneurysms, we would know more accurate indications for FD treatment, the methods to improve the FD treatment strategies and techniques and to improve the FD treatment safety in off-label usage.
Hence, we would like this Research Topic to collect studies of the safety and efficacy of the flow diverter off-label usage. Article type of the Research Topic includes Brief Research Report, Case Report, Clinical Trial, Editorial, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Study Protocol and Systematic Review.
We welcome articles concerning, but not limited to:
- Flow diverters usage in the treatment of posterior circulation aneurysms or distal artery aneurysms;
- Flow diverters usage in non-saccular aneurysms such as fusiform, ruptured (including blister-like), or traumatic aneurysms;
- Improving the safety of flow diverter treatment in the aneurysms, such as technical improvement and anti-platelet regimen.
FDs were first used in internal carotid artery large or giant unruptured aneurysms. With the excellent efficacy of FDs in the aneurysm treatment, FDs have also been used in off-label circumstances such as posterior circulation aneurysms, distal artery aneurysms, ruptured aneurysms, and traumatic aneurysms, etc. However, while the safety and efficacy of FDs in internal carotid unruptured aneurysms have been proved, the off-label use in posterior circulation, distal arteries, ruptured aneurysms, and traumatic aneurysms, etc, is still in controversy. Some studies indicated that FDs in such aneurysms are feasible and effective, but the complications were not negligible. How to decrease the complications in such aneurysms remains a great challenge for physicians. By investigating the treatment effect of FDs in such aneurysms, we would know more accurate indications for FD treatment, the methods to improve the FD treatment strategies and techniques and to improve the FD treatment safety in off-label usage.
Hence, we would like this Research Topic to collect studies of the safety and efficacy of the flow diverter off-label usage. Article type of the Research Topic includes Brief Research Report, Case Report, Clinical Trial, Editorial, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Study Protocol and Systematic Review.
We welcome articles concerning, but not limited to:
- Flow diverters usage in the treatment of posterior circulation aneurysms or distal artery aneurysms;
- Flow diverters usage in non-saccular aneurysms such as fusiform, ruptured (including blister-like), or traumatic aneurysms;
- Improving the safety of flow diverter treatment in the aneurysms, such as technical improvement and anti-platelet regimen.
Keywords: Cerebral aneurysms, Flow diverters, Pipeline embolization device, Neuro-interventional, Endovascular techniques, Embolization, Antiaggregant treatment
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
