With the rapid growth of RNAi medication research and related technologies in recent years, the research and development of RNA biopesticides based on RNAi technology have also entered a period of rapid development. Due to their high targeting accuracy, easy degradability, and environmental and pollution-free benefits, RNA biopesticides have been dubbed "the third revolution in the history of agriculture." With the launch of Bayer (Monsanto) genetically modified maize (Mon87411) and Bio Direct, RNA biopesticides have gained increasing public attention. Large-scale production of dsRNA and stability of dsRNA preparations are critical aspects of the commercialization of RNA pesticides. In the last 10 years, the cost of dsRNA production has decreased from $12000 per gram to $1. At the same time, various dsRNA coating materials can significantly increase the stability of dsRNA. These findings have the potential to accelerate the industrialization of ds-RNA-based insecticides.
This Research Topic covers the most recent breakthroughs in the field of dsRNA synthesis, the technique of ds-RNA-based pesticide application, and the strategy to increase the stability and efficiency of dsRNA. To achieve the widespread application of this technology in modern agriculture, successful examples of ds-RNA-based pesticides hurdles to be overcome, and possible approaches will be reviewed. Authors are encouraged to submit original articles with new research findings as well as review articles on the development of ds-RNA-based herbicides. Contributions summarizing regulatory bodies' opinions are also encouraged.
Some potential research topics for this Research Topic include, but are not limited to:
- Research on ds-RNA-based insecticides - Research on dsRNA synthesis
- Research on application technology of ds-RNA-based insecticides and delivery technology to enhance dsRNA efficacy.
- Research on RNAi processes and barriers in insects, and insect resistance to dsRNA.
- Developments in large-scale dsRNA production
- development of sprayable and in-plant dsRNA bioinsecticides.
- Environmental RNAi research, safety studies and regulatory views on dsRNA bioinsecticides.
- Research on the regulatory aspects of using encapsulated or pure nucleic acids for plant protection.
With the rapid growth of RNAi medication research and related technologies in recent years, the research and development of RNA biopesticides based on RNAi technology have also entered a period of rapid development. Due to their high targeting accuracy, easy degradability, and environmental and pollution-free benefits, RNA biopesticides have been dubbed "the third revolution in the history of agriculture." With the launch of Bayer (Monsanto) genetically modified maize (Mon87411) and Bio Direct, RNA biopesticides have gained increasing public attention. Large-scale production of dsRNA and stability of dsRNA preparations are critical aspects of the commercialization of RNA pesticides. In the last 10 years, the cost of dsRNA production has decreased from $12000 per gram to $1. At the same time, various dsRNA coating materials can significantly increase the stability of dsRNA. These findings have the potential to accelerate the industrialization of ds-RNA-based insecticides.
This Research Topic covers the most recent breakthroughs in the field of dsRNA synthesis, the technique of ds-RNA-based pesticide application, and the strategy to increase the stability and efficiency of dsRNA. To achieve the widespread application of this technology in modern agriculture, successful examples of ds-RNA-based pesticides hurdles to be overcome, and possible approaches will be reviewed. Authors are encouraged to submit original articles with new research findings as well as review articles on the development of ds-RNA-based herbicides. Contributions summarizing regulatory bodies' opinions are also encouraged.
Some potential research topics for this Research Topic include, but are not limited to:
- Research on ds-RNA-based insecticides - Research on dsRNA synthesis
- Research on application technology of ds-RNA-based insecticides and delivery technology to enhance dsRNA efficacy.
- Research on RNAi processes and barriers in insects, and insect resistance to dsRNA.
- Developments in large-scale dsRNA production
- development of sprayable and in-plant dsRNA bioinsecticides.
- Environmental RNAi research, safety studies and regulatory views on dsRNA bioinsecticides.
- Research on the regulatory aspects of using encapsulated or pure nucleic acids for plant protection.