Prediabetes and Endocrine Function

39.4K

views

44

authors

11

articles

Editorial

17 August 2023

Editorial: Prediabetes and endocrine function

Andile Khathi

and

Sam Dagogo-Jack

1,287 views

0 citations

Editors

2

Andile Khathi

University of KwaZulu-Natal

Sam Dagogo-Jack

University of Tennessee Health Science Center (UTHSC)

Impact

About

The onset of type 2 diabetes (T2D) is often preceded by an asymptomatic condition known as prediabetes where glucose levels are above the normal range but below the threshold for the diagnosis of T2D.

Recent studies have shown that a number of complications associated with T2D begin and progress during prediabetes. Additionally, more studies have shown that the intermediate hyperglycemia associated with prediabetes may result in chronic sub-clinical inflammation and increased generation of reactive oxygen species (ROS). This may have consequences on thyroid, renal, hepatic, and immune function, to name a few.

The effects of hyperglycemia, inflammation, and ROS generation in relation to endocrine function are well-documented in T2D, however, these effects are not yet fully understood in the prediabetic state. In this Research Topic, we welcome papers looking at the effects of prediabetes on endocrine function and how this could affect homeostasis as well as the body’s response to disease. This Topic aims to increase the understanding of fundamental aspects of prediabetes as it is a condition that can be targeted to prevent T2D and the associated complications.

Download ebook

PDF

EPUB

Share

Editors

Andile Khathi

University of KwaZulu-Natal

Sam Dagogo-Jack

University of Tennessee Health Science Center (UTHSC)

Impact

39,372 Total views

26,224 Article views

12,539 Article downloads

609 Topic views

Published In

Frontiers in Endocrinology

Clinical Diabetes

Frontiers in Public Health

Clinical Diabetes

Frontiers in Neuroscience

Clinical Diabetes

Frontiers in Nutrition

Clinical Diabetes

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic