Chlamydia trachomatis infection is the most frequently reported bacterial sexually transmitted infection (STI) globally, with an estimated 131 million new cases occurring annually. Chlamydia spreads through vaginal, anal, or oral sex with a partner with the infection. It is common among young people aged 15-24 years. However, as chlamydia infections are often asymptomatic, most infected are not aware of their infection and do not seek medical attention. This hinders the early identification and the effective clinical management of chlamydia infection, especially in developing countries. C. trachomatis infection can lead to severe complications in the absence of treatment, including tubal infertility or ectopic pregnancy, as well as facilitation of HIV transmission and infection. This underscores the importance of multi-disciplinary research to inform clinical decisions, public health control measures, surveillance, diagnostics, and prevention strategies. The high burden of chlamydia trachomatis infection observed in many countries provides unique opportunities for expanded research programs.
This Research Topic seeks to highlight the progress made in understanding chlamydia trachomatis infection, and consolidate a broad evidence base that includes clinical, epidemiology, basic science, and behavioral research to strengthen the control of chlamydia trachomatis infection globally. We invite submissions of Original Research, Reviews, and Commentaries, in the subtopics of, but not limited to:
- Epidemiology, surveillance, modelling and implementation of chlamydia trachomatis infection control.
- Chlamydia trachomatis infection clinical management.
- Persistence and immune evasion of chlamydia trachomatis.
- Protective immunity, vaccine development and barriers to vaccine acceptance.
- Natural history of Genital chlamydia trachomatis infection
- Diagnostics, especially in self-testing, self-collection, and decentralized testing of chlamydia trachomatis infection.
- Health economics
Chlamydia trachomatis infection is the most frequently reported bacterial sexually transmitted infection (STI) globally, with an estimated 131 million new cases occurring annually. Chlamydia spreads through vaginal, anal, or oral sex with a partner with the infection. It is common among young people aged 15-24 years. However, as chlamydia infections are often asymptomatic, most infected are not aware of their infection and do not seek medical attention. This hinders the early identification and the effective clinical management of chlamydia infection, especially in developing countries. C. trachomatis infection can lead to severe complications in the absence of treatment, including tubal infertility or ectopic pregnancy, as well as facilitation of HIV transmission and infection. This underscores the importance of multi-disciplinary research to inform clinical decisions, public health control measures, surveillance, diagnostics, and prevention strategies. The high burden of chlamydia trachomatis infection observed in many countries provides unique opportunities for expanded research programs.
This Research Topic seeks to highlight the progress made in understanding chlamydia trachomatis infection, and consolidate a broad evidence base that includes clinical, epidemiology, basic science, and behavioral research to strengthen the control of chlamydia trachomatis infection globally. We invite submissions of Original Research, Reviews, and Commentaries, in the subtopics of, but not limited to:
- Epidemiology, surveillance, modelling and implementation of chlamydia trachomatis infection control.
- Chlamydia trachomatis infection clinical management.
- Persistence and immune evasion of chlamydia trachomatis.
- Protective immunity, vaccine development and barriers to vaccine acceptance.
- Natural history of Genital chlamydia trachomatis infection
- Diagnostics, especially in self-testing, self-collection, and decentralized testing of chlamydia trachomatis infection.
- Health economics