Primary central nervous system (CNS) and peripheral nervous system (PNS) cancers are remarkably common in adults and children, with roughly 30 in every 100,000 developing the disease every year. This has resulted in therapies and diagnostics being developed at an ever-increasing rate to help treat the disease. However, tumors of the CNS and PNS can be complex, with several subtypes associated with this category of malignancy. Roughly 6 in every 100,000 develop these rare tumors every year. Despite the efforts and care improvement dedicated to the most diffused brain and spine tumors (such as glioblastomas, metastases, or meningiomas), some of these diseases still lack defined management plans or specific preclinical assessment of their cellular/molecular features. Moreover, due to their rarity, progress in biological and clinical research is slow in most cases.
The current Special Issues is addressed to collect information about clinical and surgical management, new diagnostic techniques (pre-, post-, and intraoperative), new drugs and innovative therapeutic therapies, as well as about preclinical studies based on genetic, cellular, molecular, or "omics" approaches, dedicated to rare tumors of the central and peripheral nervous system in both pediatric and adult tumor types.
For example, for pediatric cases: Choroid plexus carcinomas, Chordomas, Meningiomas, Dysembryoplastic Neuroepithelial Tumors (DNETs), Ganglioglioma, Craniopharyngiomas, Medulloepithelioma, Atypical teratoid/rhabdoid tumor (ATRT), Focal brain stem gliomas, Oligodendrogliomas and other unique and rare pediatric brain tumors
For adult tumor types, manuscripts about Pilocytic astrocytomas, Glioneuronal tumors, Optic pathway gliomas (with/without type 1 neurofibromatosis), Hemangioblastomas, Ependymoma, Pineal tumors, Schwannomas, Neurofibromas, MPNST are also welcome.
In this Research Topic, we intend to collate key research findings in the field of the management and understanding of CNS & PNS tumors and invite contributions in the form of Original Research articles, Reviews, Case Reports, and Clinical Trials relating to our current understanding, advancement and future therapies/management of these rare diseases.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Primary central nervous system (CNS) and peripheral nervous system (PNS) cancers are remarkably common in adults and children, with roughly 30 in every 100,000 developing the disease every year. This has resulted in therapies and diagnostics being developed at an ever-increasing rate to help treat the disease. However, tumors of the CNS and PNS can be complex, with several subtypes associated with this category of malignancy. Roughly 6 in every 100,000 develop these rare tumors every year. Despite the efforts and care improvement dedicated to the most diffused brain and spine tumors (such as glioblastomas, metastases, or meningiomas), some of these diseases still lack defined management plans or specific preclinical assessment of their cellular/molecular features. Moreover, due to their rarity, progress in biological and clinical research is slow in most cases.
The current Special Issues is addressed to collect information about clinical and surgical management, new diagnostic techniques (pre-, post-, and intraoperative), new drugs and innovative therapeutic therapies, as well as about preclinical studies based on genetic, cellular, molecular, or "omics" approaches, dedicated to rare tumors of the central and peripheral nervous system in both pediatric and adult tumor types.
For example, for pediatric cases: Choroid plexus carcinomas, Chordomas, Meningiomas, Dysembryoplastic Neuroepithelial Tumors (DNETs), Ganglioglioma, Craniopharyngiomas, Medulloepithelioma, Atypical teratoid/rhabdoid tumor (ATRT), Focal brain stem gliomas, Oligodendrogliomas and other unique and rare pediatric brain tumors
For adult tumor types, manuscripts about Pilocytic astrocytomas, Glioneuronal tumors, Optic pathway gliomas (with/without type 1 neurofibromatosis), Hemangioblastomas, Ependymoma, Pineal tumors, Schwannomas, Neurofibromas, MPNST are also welcome.
In this Research Topic, we intend to collate key research findings in the field of the management and understanding of CNS & PNS tumors and invite contributions in the form of Original Research articles, Reviews, Case Reports, and Clinical Trials relating to our current understanding, advancement and future therapies/management of these rare diseases.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
