About this Research Topic
Tightly linked to tissue engineering and regenerative medicine, genetic and cellular therapies have drawn universal attention. Since genetic sequencing is critical for precision medicine, the combination of bioinformatics and therapies is important to conduct prescriptive and predictive analytics based on genetic sequencing data. Bioinformatics and computational approaches have been widely considered for the development of genetic and cellular therapies. Therefore, the current research topic aims to cover recent advances in studies such as functional genomics, proteomics, metabolomics, and bioinformatics that bring in new perspectives on genetic therapies.
The central goal of regenerative medicine is to replace damaged or diseased tissue with cells that are integrated and functioning optimally. Stem cell-based therapy is restricted by the limited availability of cell sources, the excessive cost, and the anticipated difficulties of clinical translation and ethical approval. Some promising alternatives are to incite the patient's innate ability of tissue repairs such as in situ tissue regeneration, which has the potential to provide new therapeutic options for tissue engineering and regenerative medicine. These innovative cellular therapies are also contained in our research topic.
Authors are invited to submit a manuscript. Relevant topics of interest to this special section include (but are not limited to):
• Application of cellular therapies for tissue engineering and regenerative medicine, such as wound healing, fracture repair, et al;
• Development of cellular therapies that are transformative to tissue engineering and regenerative medicine;
• Advanced bioinformatics approaches for drugs and advanced materials discovery, and therapeutics in tissue repair and regeneration together with sufficient experimental validation to support your points;
• Bioinformatic analysis on extracellular vesicle/exosome and microRNAs biomarkers and their tissue engineering application in genetic therapies together with sufficient experimental validation;
• Bioinformatic analysis on DNA methylation, and epigenetic biomarkers and their tissue engineering application in genetic therapies together with sufficient experimental validation;
• The innovative reviews concerning genetic and cellular therapies in tissue engineering and regenerative medicine area.
The central goal of regenerative medicine is to replace damaged or diseased tissue with cells that are integrated and functioning optimally. Stem cell-based therapy is restricted by the limited availability of cell sources, the excessive cost, and the anticipated difficulties of clinical translation and ethical approval. Some promising alternatives are to incite the patient's innate ability of tissue repairs such as in situ tissue regeneration, which has the potential to provide new therapeutic options for tissue engineering and regenerative medicine. These innovative cellular therapies are also contained in our research topic.
Authors are invited to submit a manuscript. Relevant topics of interest to this special section include (but are not limited to):
• Application of cellular therapies for tissue engineering and regenerative medicine, such as wound healing, fracture repair, et al;
• Development of cellular therapies that are transformative to tissue engineering and regenerative medicine;
• Advanced bioinformatics approaches for drugs and advanced materials discovery, and therapeutics in tissue repair and regeneration together with sufficient experimental validation to support your points;
• Bioinformatic analysis on extracellular vesicle/exosome and microRNAs biomarkers and their tissue engineering application in genetic therapies together with sufficient experimental validation;
• Bioinformatic analysis on DNA methylation, and epigenetic biomarkers and their tissue engineering application in genetic therapies together with sufficient experimental validation;
• The innovative reviews concerning genetic and cellular therapies in tissue engineering and regenerative medicine area.
Keywords: tissue engineering, regenerative medicine, bioinformatics, cellular therapies, drug discovery, biomarkers, genetic therapies
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
