The innovation of green pesticide is an important direction and mainstream of modern agricultural chemistry. As the important part for innovation of green pesticide, heterocyclic compounds show an important role in the development of pesticides due to the good selectivity, high activity, low dosage, low toxicity, and specificity in the biochemical and physiological properties. In the past decade, more than 50 novel green pesticides containing the heterocyclic substructures (such as fluazifop, flupoxan, Fluazinam, fluopyram, fluopicolide, flumethrin etc.) were launched, and many lead compounds or candidates have emerged. The important position of heterocyclic molecules in the pesticides market is supposed to remain in the following decades. Moreover, considerable progress has been made in green pesticide screening model, rational design of pesticides, the research, and the application of immune inducers for plants. Among the newly listed pesticides, there are many new mechanisms and new target products have been reported one after another. In particular, the guidance of new biotechnology, the application of bioinformation technology and multidisciplinary promotion have been gradually integrated into green pesticide innovation, which has become the distinctive feature of the new round of pesticide science. Remarkable achievements have been made in the innovation of green pesticides based on the heterocyclic compound and potential targets, such as rational design of heterocyclic pesticide, biomimetic synthesis, mining, discovery, and verification of molecular targets.
Consequently, this Research Topic on "Advances in the Green Synthesis of Heterocyclic compounds for Pesticides" will highlight current progress on the development of heterocyclic molecules in the innovation of green pesticide. We welcome original research articles, reviews, perspectives, and mini-reviews which focus on (but are not limiting to) the following themes:
• New synthetic strategies to heterocyclic molecules with potential pesticidal activity
• Green approaches to the synthesis of heterocyclic molecules
• The design and the organic synthesis / isolation of new chemical compounds with pesticidal activity
• Founding and action mechanism of molecular targets of heterocyclic pesticides
The innovation of green pesticide is an important direction and mainstream of modern agricultural chemistry. As the important part for innovation of green pesticide, heterocyclic compounds show an important role in the development of pesticides due to the good selectivity, high activity, low dosage, low toxicity, and specificity in the biochemical and physiological properties. In the past decade, more than 50 novel green pesticides containing the heterocyclic substructures (such as fluazifop, flupoxan, Fluazinam, fluopyram, fluopicolide, flumethrin etc.) were launched, and many lead compounds or candidates have emerged. The important position of heterocyclic molecules in the pesticides market is supposed to remain in the following decades. Moreover, considerable progress has been made in green pesticide screening model, rational design of pesticides, the research, and the application of immune inducers for plants. Among the newly listed pesticides, there are many new mechanisms and new target products have been reported one after another. In particular, the guidance of new biotechnology, the application of bioinformation technology and multidisciplinary promotion have been gradually integrated into green pesticide innovation, which has become the distinctive feature of the new round of pesticide science. Remarkable achievements have been made in the innovation of green pesticides based on the heterocyclic compound and potential targets, such as rational design of heterocyclic pesticide, biomimetic synthesis, mining, discovery, and verification of molecular targets.
Consequently, this Research Topic on "Advances in the Green Synthesis of Heterocyclic compounds for Pesticides" will highlight current progress on the development of heterocyclic molecules in the innovation of green pesticide. We welcome original research articles, reviews, perspectives, and mini-reviews which focus on (but are not limiting to) the following themes:
• New synthetic strategies to heterocyclic molecules with potential pesticidal activity
• Green approaches to the synthesis of heterocyclic molecules
• The design and the organic synthesis / isolation of new chemical compounds with pesticidal activity
• Founding and action mechanism of molecular targets of heterocyclic pesticides
