Endocrine and metabolic disorders affect various organs, and profoundly impair the quality of human life. While treatments have been developed these years, novel therapeutic targets still need to be identified. Mitochondria play a central role in energy metabolism, providing energy in the form of ATP, and are critical organelles for maintaining endocrine and metabolic health. Mitochondrial dysfunctions causing defective energy metabolism result in critical clinical manifestations. Mitochondria are morphologically and functionally diverse in different endocrine organs, and can also contribute to cell-cell crosstalk via intercellular trafficking. Endocrine disorders including osteoporosis, diabetes, hypogonadism, adrenal dysfunction, hyperparathyroidism, and thyroid disease, are often associated with various mitochondrial dysfunctions. Understanding mitochondrial metabolism will be key to approaching innovative therapies for endocrine disorders.
With this Research Topic, we aim to provide an overview of what is known about the relationship between mitochondrial metabolism and endocrine disorders, the latest opinions on the role of mitochondrial heterogeneity, and mitochondrial trafficking-related intercell or interorgan regulation in various endocrine disorders, to highlight novel therapies.
This Research Topic aims to focus on the most recent advancements in the field, covering both basic and clinical aspects, and calls for submissions of Original Research, Reviews, Case studies, and Methods, as listed but not limited to the following:
• Energy metabolism in endocrine disorders
• Role of mitochondrial trafficking in endocrine disorders
• Cell-cell crosstalk in endocrine disorders
• Interorgan regulation in endocrine disorders
• Role of mitochondrial heterogeneity in endocrine disorders
To the contributors of this Research Topic: please choose Dr. Junjie Gao as the Preferred Handling Editor when submitting your manuscript. Dr. Junjie Gao will ensure your submission is assigned to the most suitable Topic Editor.
Endocrine and metabolic disorders affect various organs, and profoundly impair the quality of human life. While treatments have been developed these years, novel therapeutic targets still need to be identified. Mitochondria play a central role in energy metabolism, providing energy in the form of ATP, and are critical organelles for maintaining endocrine and metabolic health. Mitochondrial dysfunctions causing defective energy metabolism result in critical clinical manifestations. Mitochondria are morphologically and functionally diverse in different endocrine organs, and can also contribute to cell-cell crosstalk via intercellular trafficking. Endocrine disorders including osteoporosis, diabetes, hypogonadism, adrenal dysfunction, hyperparathyroidism, and thyroid disease, are often associated with various mitochondrial dysfunctions. Understanding mitochondrial metabolism will be key to approaching innovative therapies for endocrine disorders.
With this Research Topic, we aim to provide an overview of what is known about the relationship between mitochondrial metabolism and endocrine disorders, the latest opinions on the role of mitochondrial heterogeneity, and mitochondrial trafficking-related intercell or interorgan regulation in various endocrine disorders, to highlight novel therapies.
This Research Topic aims to focus on the most recent advancements in the field, covering both basic and clinical aspects, and calls for submissions of Original Research, Reviews, Case studies, and Methods, as listed but not limited to the following:
• Energy metabolism in endocrine disorders
• Role of mitochondrial trafficking in endocrine disorders
• Cell-cell crosstalk in endocrine disorders
• Interorgan regulation in endocrine disorders
• Role of mitochondrial heterogeneity in endocrine disorders
To the contributors of this Research Topic: please choose Dr. Junjie Gao as the Preferred Handling Editor when submitting your manuscript. Dr. Junjie Gao will ensure your submission is assigned to the most suitable Topic Editor.
