Cells are the fundamental units of life. Life develops from a single cell and differentiates into various cell lineages. Even though cells may be morphologically and genetically identical, recent findings shows that they are heterogeneous with dramatic differences. Cell-based assays are only able to capture a snapshot of the average functions of a group of cells, without regarding individual cell types. A thorough understanding of individual cells can give us ground-breaking insights as these cells may play key roles in health and disease.
Recent advances in various techniques have allowed us to investigate a single cell and to understand its structure and function. These innovations have paved the way to reliably investigate genomics, epigenomics, transcriptomics, proteomics, secretomics, metabolomics, and cell communications at the single cell level. Advances in multiomics technologies, coupled with various novel computing tools to process this data, has opened a new era in single cell analysis. Other technologies have been rapidly evolving to assist in single cell analysis including cell isolation, DNA/RNA sequencing, microscopy, mass-spectrometry, microfluidics, flow cytometry etc.
Single cell analysis stands to unlock various mysteries of the structure and functions of stem cells, gametes, embryos, endocrine cells, and other metabolically active cells pertaining to endocrinology, reproduction, and metabolism. The aim of this collection is to bring together and give a platform to publish the latest cutting-edge innovations using single cell analysis.
This Research Topic will highlight technical advances as well as novel findings in single cell research applied in the field of endocrinology, reproduction, and metabolism in the form of Original Research, Review, Mini-Review and Perspective articles.
This special edition will accept manuscripts on the following topics:
• Novel methodologies that are applicable in endocrinology, reproduction, and metabolism;
• Single cell ‘omics’ including multiomics and bioinformatics;
• Structural and functional analysis of endocrine cells;
• Stem cells, gamete and embryo biology; and
• Single cell analysis of mitosis and meiosis.
Cells are the fundamental units of life. Life develops from a single cell and differentiates into various cell lineages. Even though cells may be morphologically and genetically identical, recent findings shows that they are heterogeneous with dramatic differences. Cell-based assays are only able to capture a snapshot of the average functions of a group of cells, without regarding individual cell types. A thorough understanding of individual cells can give us ground-breaking insights as these cells may play key roles in health and disease.
Recent advances in various techniques have allowed us to investigate a single cell and to understand its structure and function. These innovations have paved the way to reliably investigate genomics, epigenomics, transcriptomics, proteomics, secretomics, metabolomics, and cell communications at the single cell level. Advances in multiomics technologies, coupled with various novel computing tools to process this data, has opened a new era in single cell analysis. Other technologies have been rapidly evolving to assist in single cell analysis including cell isolation, DNA/RNA sequencing, microscopy, mass-spectrometry, microfluidics, flow cytometry etc.
Single cell analysis stands to unlock various mysteries of the structure and functions of stem cells, gametes, embryos, endocrine cells, and other metabolically active cells pertaining to endocrinology, reproduction, and metabolism. The aim of this collection is to bring together and give a platform to publish the latest cutting-edge innovations using single cell analysis.
This Research Topic will highlight technical advances as well as novel findings in single cell research applied in the field of endocrinology, reproduction, and metabolism in the form of Original Research, Review, Mini-Review and Perspective articles.
This special edition will accept manuscripts on the following topics:
• Novel methodologies that are applicable in endocrinology, reproduction, and metabolism;
• Single cell ‘omics’ including multiomics and bioinformatics;
• Structural and functional analysis of endocrine cells;
• Stem cells, gamete and embryo biology; and
• Single cell analysis of mitosis and meiosis.
