Research has indicated that as we age, the functionality of neural networks alters. Age-related changes in cognition can differ according to sex differences, possibly due to the difference between the sexes in the organization of the brain. Studying these sex differences can help delineate neuropsychological pathways and highlight neural differences and similarities.
Previous studies found that age-related changes are more apparent in men, making them more vulnerable to cognitive decline. For example, gray matter atrophy either starts earlier or is more rapid for men. Additionally, there is evidence of female mice models with increased sensory-discriminative pain, even after the onset of Alzheimer’s Disease, than male mice. Understanding the differences in neurocognitive aging can help guide specific treatments for neurodegenerative diseases. The ever-increasing aging population has highlighted the need to study these sex differences.
This Research Topic is looking to address key aspects of sex differences in age-related alterations in cognition and behavior to promote discussion around this topic. It will be used as a platform to call attention to the latest novel research that highlights sex differences in cognitive decline and vulnerability to neurodegenerative disease. We hope the research uncovered by this collection will help to provide innovative tailored care solutions.
We particularly welcome submissions of Original Research, Review, Methods, and Perspective articles on the following sub-topics:
• Sex differences in age-related changes in organizational neural networks and their related effect on cognition
• Vulnerability and occurrence of neurodegenerative disease mediated by sex differences
• Sex differences in cellular and molecular atrophy
• Neuroimaging of the difference in neural activity and network associated with cognitive decline
• Differences in the pathology of neurogenerative diseases.
Research has indicated that as we age, the functionality of neural networks alters. Age-related changes in cognition can differ according to sex differences, possibly due to the difference between the sexes in the organization of the brain. Studying these sex differences can help delineate neuropsychological pathways and highlight neural differences and similarities.
Previous studies found that age-related changes are more apparent in men, making them more vulnerable to cognitive decline. For example, gray matter atrophy either starts earlier or is more rapid for men. Additionally, there is evidence of female mice models with increased sensory-discriminative pain, even after the onset of Alzheimer’s Disease, than male mice. Understanding the differences in neurocognitive aging can help guide specific treatments for neurodegenerative diseases. The ever-increasing aging population has highlighted the need to study these sex differences.
This Research Topic is looking to address key aspects of sex differences in age-related alterations in cognition and behavior to promote discussion around this topic. It will be used as a platform to call attention to the latest novel research that highlights sex differences in cognitive decline and vulnerability to neurodegenerative disease. We hope the research uncovered by this collection will help to provide innovative tailored care solutions.
We particularly welcome submissions of Original Research, Review, Methods, and Perspective articles on the following sub-topics:
• Sex differences in age-related changes in organizational neural networks and their related effect on cognition
• Vulnerability and occurrence of neurodegenerative disease mediated by sex differences
• Sex differences in cellular and molecular atrophy
• Neuroimaging of the difference in neural activity and network associated with cognitive decline
• Differences in the pathology of neurogenerative diseases.
