About this Research Topic
A research topic for Frontiers in Aging Neuroscience is proposed that will address neuroimaging for the study and assessment of cognitive aging. While there have been numerous neuroimaging studies of Alzheimer’s disease and other neurodegenerative diseases over the past three decades, the scientific literature on neuroimaging in the context of normal cognitive aging is still relatively nascent, particularly with respect to normative data on oldest old and successful aging. Certain neuroimaging modalities have been studied more extensively in this regard, though there is a need for a thematic presentation on this topic that covers the various neuroimaging modalities that are currently being investigated. There is a growing literature linking specific neuroimaging indices to laboratory biomarkers and also cognitive measures in the context of aging. There is a need for an integrated presentation of the type being proposed for this research topic in Frontiers in Aging Neuroscience to address this topic.
The McKnight Brain Institutes at the Universities of Florida, Arizona, Alabama-Birmingham, and Miami consists of a number of well-established senior investigators who have been engaged in research of relevance to this topic with the overarching goal of establishing a McKnight Aging Brain Registry. We are conducting inter-institute studies of successful cognitive aging in the oldest-old. This collaborative research effort provides the foundation for the proposed research topic.
We welcome the submission of manuscripts that address the application of specific neuroimaging modalities to cognitive aging. These papers will provide valuable information for researchers regarding age-associated structural and functional brain changes that are associated with cognitive aging, and the potential value of particular neuroimaging measures as biomarkers of these changes. We will also identify gaps in current knowledge regarding age-related brain changes that can be derived from neuroimaging methods and provide recommendations for addressing these gaps.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.