Neuroimmune interface in health and diseases

130.9K

views

49

authors

15

articles

Editorial

23 October 2017

Editorial: Neuroimmune Interface in Health and Diseases

Ihssane Zouikr

,

Sanae Hasegawa-Ishii

and

Atsuyoshi Shimada

3,241 views

3 citations

Editors

3

Southern Cross University

Atsuyoshi Shimada

Kyorin University

Sanae Hasegawa-Ishii

Faculty of Health Sciences, Kyorin University

Impact

About

It is now well appreciated that the immune system, in addition to its traditional role in defending the organism against ubiquitous pathogens, communicate in a very organized fashion with the brain to regulate a set of physiological behaviours. Perturbing this immune to brain communication for instance in the case of bacterial/viral infection can cause long-term alterations in immune and neuronal (spinal and supraspinal) responses, leading to altered behavioural and psychological disorders (i.e. increased pain sensitivity, altered emotional responses, autism etc...) later in life.

How neonatal and adult inflammatory challenge can lead to altered immune and neuronal responses and which immune cells both at the periphery and the central nervous system contribute to this neuroinflammation is the aim of this topic. A big focus will be dedicated to the role of neuroimmune interface in health and disease (with particular focus on pain).

It is now well appreciated that the immune system, in addition to its traditional role in defending the organism against ubiquitous pathogens, communicate in a very organized fashion with the brain to regulate a set of physiological behaviours. Perturbing this immune to brain communication for instance in the case of bacterial/viral infection can cause long-term alterations in immune and neuronal (spinal and supraspinal) responses, leading to altered behavioural and psychological disorders (i.e. increased pain sensitivity, altered emotional responses, autism etc...) later in life.

How neonatal and adult inflammatory challenge can lead to altered immune and neuronal responses and which immune cells both at the periphery and the central nervous system contribute to this neuroinflammation is the aim of this topic. A big focus will be dedicated to the role of neuroimmune interface in health and disease (with particular focus on pain).

Download ebook

Share

Editors

Southern Cross University

Atsuyoshi Shimada

Kyorin University

Sanae Hasegawa-Ishii

Faculty of Health Sciences, Kyorin University

Impact

130,853 Total views

96,455 Article views

30,130 Article downloads

4,268 Topic views

Published In

Journal Thumbnail

Frontiers in Immunology

Multiple Sclerosis and Neuroimmunology

Journal Thumbnail

Frontiers in Neurology

Multiple Sclerosis and Neuroimmunology

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic