Advanced Approaches in the Diagnosis and Treatment of Diabetes Mellitus and Secondary Complications

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350

authors

46

articles

Advanced Approaches in the Diagnosis and Treatment of Diabetes Mellitus and Secondary Complications

181K

views

350

authors

46

articles

Editorial

20 September 2023

Editorial: Advanced approaches in the diagnosis and treatment of diabetes mellitus and secondary complications

Ponnurengam Malliappan Sivakumar

,

Ram Prasad

and

Pranav Kumar Prabhakar

1,841 views

0 citations

Editors

3

Pranav Kumar Prabhakar

Parul University

University of Alabama at Birmingham

Ponnurengam Malliappan Sivakumar

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About

As we know diabetes mellitus is the most common metabolic endocrine disorder. According to the WHO and American Diabetes Mellitus, diabetes mellitus is the 3rd leading cause of death if we were to include all secondary complications. However without including secondary complications, it is 7th place in mortality and morbidity. The point to be considered in the case of diabetes mellitus is the secondary complications caused in this condition. Almost all organs affected by diabetes and results in a potentially worse condition. The major secondary complications are neuropathy, nephropathy, retinopathy, and diabetes foot microvascular and macrovascular complications. The long term complications grow slowly in the case of diabetes. As the time living with diabetes becomes longer, controlled glucose levels will be more difficult to achieve, meaning there there will be more long term complications.

The aim of the current Research Topic on the secondary complications of diabetes and their management is to publish good quality research articles as well as reviews, which should address the management of diabetes, abnormalities of secondary complications and other disease involved in diabetes.

Potential Topics includes but not restricted to:

• Secondary complications of diabetes mellitus

• Microvascular and macrovascular complications

• The role of oxidative stress in the diabetes burden

• New insights in glycemic control

• New strategies/ approaches to manage secondary complications such as Stearoyl CoA dismutase, Acetyl CoA Carboxylase, Adiponectin/ Adipocyte complement-related protein 30, Hormone Sensitive Lipase (HSL) Inhibitors

• Recent development in the therapeutic approaches for glucose management such as Protein tyrosine phosphatase-1B (PTP1B) inhibitors, Glycogen synthase kinase-3 (GSK3) inhibitors, ß3- Adrenergic receptor agonist, Retinoid X receptor, PPARa agonist, AMP activated protein kinase

• Development of new target as a target for antihyperglycemic drug designing

As we know diabetes mellitus is the most common metabolic endocrine disorder. According to the WHO and American Diabetes Mellitus, diabetes mellitus is the 3rd leading cause of death if we were to include all secondary complications. However without including secondary complications, it is 7th place in mortality and morbidity. The point to be considered in the case of diabetes mellitus is the secondary complications caused in this condition. Almost all organs affected by diabetes and results in a potentially worse condition. The major secondary complications are neuropathy, nephropathy, retinopathy, and diabetes foot microvascular and macrovascular complications. The long term complications grow slowly in the case of diabetes. As the time living with diabetes becomes longer, controlled glucose levels will be more difficult to achieve, meaning there there will be more long term complications.

The aim of the current Research Topic on the secondary complications of diabetes and their management is to publish good quality research articles as well as reviews, which should address the management of diabetes, abnormalities of secondary complications and other disease involved in diabetes.

Potential Topics includes but not restricted to:

• Secondary complications of diabetes mellitus

• Microvascular and macrovascular complications

• The role of oxidative stress in the diabetes burden

• New insights in glycemic control

• New strategies/ approaches to manage secondary complications such as Stearoyl CoA dismutase, Acetyl CoA Carboxylase, Adiponectin/ Adipocyte complement-related protein 30, Hormone Sensitive Lipase (HSL) Inhibitors

• Recent development in the therapeutic approaches for glucose management such as Protein tyrosine phosphatase-1B (PTP1B) inhibitors, Glycogen synthase kinase-3 (GSK3) inhibitors, ß3- Adrenergic receptor agonist, Retinoid X receptor, PPARa agonist, AMP activated protein kinase

• Development of new target as a target for antihyperglycemic drug designing

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Editors

Pranav Kumar Prabhakar

Parul University

University of Alabama at Birmingham

Ponnurengam Malliappan Sivakumar

Impact

180,976 Total views

119,400 Article views

59,699 Article downloads

1,877 Topic views

Published In

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Frontiers in Endocrinology

Clinical Diabetes

Journal Thumbnail

Frontiers in Public Health

Clinical Diabetes

Journal Thumbnail

Frontiers in Neuroscience

Clinical Diabetes

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Frontiers in Nutrition

Clinical Diabetes

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