A great part of veterinary research is focused on regenerative medicine, in which animals have always served as a basis to human research. Several species are used as experimental models for human diseases, such as horses, pigs, rats and rabbits, mostly due to the physiological and pathological similarities they share with the human musculoskeletal system. Some of the conditions include synovitis, arthritis, osteoarthritis, chondral defects, fractures, tendonitis, desmitis, among others. In this sense, regenerative therapies usually provide significant outcomes. However, this field is relatively new, demanding additional research to elucidate the cellular and molecular mechanisms of action of these therapies.
Even though several animal species are used as experimental models for musculoskeletal diseases, there is a lack of a specific topics in this field in the literature. This topic will reunite the most recent techniques and findings in regenerative medicine applied to orthopaedics, serving as a basis for further discussions on the future perspectives of this growing area. Recent techniques include cell-based therapies as 3D printed scaffolds, tissue engineering and biocomponents, applied to both human and veterinary medicine aiming to enhance not only the tissue's aspect, functionality, and longevity, but also the human and animal welfare.
This Research Topic aims to reunite high-quality research on recent findings in the field of Regenerative Medicine applied to Orthopaedics, highlighting, and arising discussion on the recent advances of this field. Original research articles, meta-analyses, mini-review, and review articles, among others, are welcomed. Potential topics include, but are not limited to, the following:
- Mesenchymal Stem Cells
- iPS - Pluripotent Stem Cells
- Platelet Rich Plasma
- Platelet Lysate
-Tissue Engineering
- Scaffolds and Biocomponents
– Gene Therapies -Immunomodulatory therapies
- Cell-therapy immunogenicity
- Preclinical trials
- In vitro and in vivo studies
- Clinical Trials
A great part of veterinary research is focused on regenerative medicine, in which animals have always served as a basis to human research. Several species are used as experimental models for human diseases, such as horses, pigs, rats and rabbits, mostly due to the physiological and pathological similarities they share with the human musculoskeletal system. Some of the conditions include synovitis, arthritis, osteoarthritis, chondral defects, fractures, tendonitis, desmitis, among others. In this sense, regenerative therapies usually provide significant outcomes. However, this field is relatively new, demanding additional research to elucidate the cellular and molecular mechanisms of action of these therapies.
Even though several animal species are used as experimental models for musculoskeletal diseases, there is a lack of a specific topics in this field in the literature. This topic will reunite the most recent techniques and findings in regenerative medicine applied to orthopaedics, serving as a basis for further discussions on the future perspectives of this growing area. Recent techniques include cell-based therapies as 3D printed scaffolds, tissue engineering and biocomponents, applied to both human and veterinary medicine aiming to enhance not only the tissue's aspect, functionality, and longevity, but also the human and animal welfare.
This Research Topic aims to reunite high-quality research on recent findings in the field of Regenerative Medicine applied to Orthopaedics, highlighting, and arising discussion on the recent advances of this field. Original research articles, meta-analyses, mini-review, and review articles, among others, are welcomed. Potential topics include, but are not limited to, the following:
- Mesenchymal Stem Cells
- iPS - Pluripotent Stem Cells
- Platelet Rich Plasma
- Platelet Lysate
-Tissue Engineering
- Scaffolds and Biocomponents
– Gene Therapies -Immunomodulatory therapies
- Cell-therapy immunogenicity
- Preclinical trials
- In vitro and in vivo studies
- Clinical Trials
