About this Research Topic
Given the complex mechanism of the ARGs transfer, the ARGs or bacteria inevitably transferred to other hosts. It is an urgent problem to illustrate the antimicrobial resistance (AMR) Enterobacteriaceae relationship among animals, humans, and environments. It is vital that expand epidemiological data about the Enterobacteriaceae bacteria with the resistance phenotype and ARGs that could find out the potential transmission mechanisms. In addition, developing advanced sequencing technologies revokes a new way of understating emerging pathogens. Thus, the routine surveillance application of this method in the One-Health issue is encouraged. Currently, the attention focuses on the resistance genes for clinically significant antibiotics, such as mcr, blaNDM, blaKPC, and tet(X) gene in E. coli, K. pneumoniae, Shigella, and Salmonella. Based on this, the effective prevention measure for ARG spread could be proposed that protect public health.
In this Research Topic, we intend to pay special attention and consideration to the following studies, which include, but are not limited to:
- Prevalence and diversity of ARGs (especially mcr, blaNDM, blaKPC, and tet(X) gene) in animals, humans and environments.
- Mechanism of mcr, blaNDM, blaKPC, and tet(X) gene transfer among Enterobacteriaceae bacteria.
- Impact of antibiotic residues leading to the change of MDR bacteria in animals and environments.
- ARGs and virulence genes association in different pathogenic bacteria.
- AMR and ARGs of pathogenic bacteria in the aquatic environment.
Keywords: Enterobacteriaceae, antimicrobial resistance, plasmid, One-Health, genome sequence
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