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Chronic pain, mental health disorders, and cognitive and memory dysfunctions are common and often overlap in the general population across the lifespan. Epidemiological and review studies have proposed a bidirectional relationship between these conditions. Functional imaging studies have suggested that this ...

Chronic pain, mental health disorders, and cognitive and memory dysfunctions are common and often overlap in the general population across the lifespan. Epidemiological and review studies have proposed a bidirectional relationship between these conditions. Functional imaging studies have suggested that this relationship is in part explained by the shared neural mechanisms involved in pain processing, mood disorders, and cognitive impairment. This phenomenon could necessitate targeted pharmacological and behavioral interventions with the aim to treat both these conditions.

Despite the improvement and the growth of interest in researching this topic, there is still a long way to go and many features need to be better understood regarding the etiopathogenesis and the treatment of these conditions. The aims of this Research Topic will be focused on:

1) Literature overview about the topic: the state of the art in the field of neuropsychiatric diseases and chronic pain

2)Which are the pathophysiological mechanisms shared by these medical conditions

3)What are considered the age ranges at risk of developing both of these conditions

4)How treatment of one condition might affect the other concomitant comorbidities

This Research Topic aims to promote the discussion around this topic and facilitate knowledge dissemination, increase our understanding of pain and mood disorders and also consider neuroanatomy evaluation. We encourage authors to contribute with original articles, review articles, or perspectives with the aim to obtain innovative and emerging treatments moving from bench to bedside.

Keywords: Pain Anxiety, Depression, Alzheimer disease, Parkinson disease


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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