Asthma is the most common chronic respiratory disorder in children. Although many papers have been published on this topic, there is still a great need to further understand the disease. The pathophysiology and the long-term prognosis of preschool wheezing are still unclear, which may be due to the heterogeneity of the disorder. In addition, the management of childhood asthma, especially severe asthma, has been mimicked from the management of adulthood asthma. Furthermore, geographic differences both in the prevalence and the severity of the disease have also been noted. Long-term outcomes in adulthood and a possible relation with chronic respiratory diseases have been identified. Given the various factors involved, further understanding of the pathophysiology and its relationship with accompanying infections may make it easier to understand the disease. An understanding of primary and secondary prevention issues is also vital to decrease the burden of the disease.
The goal of this Research Topic is to focus on the unclarified areas of asthma and to give readers a better understanding of the disease. Themes to be explored include recurrent bronchiolitis and preschool wheezing, the relation of preschool wheeze with viral infections such as RSV and rhinovirus and with bacterial infections like Moraxella catarrhalis in different populations and settings, the definition of severe asthma, and the management of the disease and accompanying illnesses. We also wish to explore the long-term outcomes of asthmatic and preschool wheezing children.
In this article collection, case studies, original studies, and reviews are all welcome. Topics to be explored may include:
• Pathophysiology of recurrent bronchiolitis and preschool wheeze
• Immunologic mechanisms of preschool wheeze
• Management of preschool wheeze
• Environmental factors and asthma
• Primary prevention of asthma
• Secondary prevention of asthma
• Infections and asthma
• COVID and asthma
• Natural course of the wheezing disorders
• Management of asthma
• Severe asthma
• Long-term prognosis of asthma
• Correlation between wheezing disorders and asthma
• Active and passive smoking and asthma
Asthma is the most common chronic respiratory disorder in children. Although many papers have been published on this topic, there is still a great need to further understand the disease. The pathophysiology and the long-term prognosis of preschool wheezing are still unclear, which may be due to the heterogeneity of the disorder. In addition, the management of childhood asthma, especially severe asthma, has been mimicked from the management of adulthood asthma. Furthermore, geographic differences both in the prevalence and the severity of the disease have also been noted. Long-term outcomes in adulthood and a possible relation with chronic respiratory diseases have been identified. Given the various factors involved, further understanding of the pathophysiology and its relationship with accompanying infections may make it easier to understand the disease. An understanding of primary and secondary prevention issues is also vital to decrease the burden of the disease.
The goal of this Research Topic is to focus on the unclarified areas of asthma and to give readers a better understanding of the disease. Themes to be explored include recurrent bronchiolitis and preschool wheezing, the relation of preschool wheeze with viral infections such as RSV and rhinovirus and with bacterial infections like Moraxella catarrhalis in different populations and settings, the definition of severe asthma, and the management of the disease and accompanying illnesses. We also wish to explore the long-term outcomes of asthmatic and preschool wheezing children.
In this article collection, case studies, original studies, and reviews are all welcome. Topics to be explored may include:
• Pathophysiology of recurrent bronchiolitis and preschool wheeze
• Immunologic mechanisms of preschool wheeze
• Management of preschool wheeze
• Environmental factors and asthma
• Primary prevention of asthma
• Secondary prevention of asthma
• Infections and asthma
• COVID and asthma
• Natural course of the wheezing disorders
• Management of asthma
• Severe asthma
• Long-term prognosis of asthma
• Correlation between wheezing disorders and asthma
• Active and passive smoking and asthma
