It is estimated that by 2050, more than 20% of the world's population will be over 60 years old, which could impose a huge economic, medical and financial burden on society. With the increase of age, there is a progressive increase of proinflammatory response state in the body. During the aging process, this defensive inflammatory response may overreact, leading to damage the body and thus to various diseases such as osteoporosis, rheumatoid arthritis, osteoarthritis, and sarcopenia. However, the pathogenesis of inflammation and aging related diseases remains unclear, and it is generally believed that it may be the result of a combination of genetic, environmental and immune abnormalities. Among these factors, the impact of immune abnormalities in these diseases has been widely and deeply discussed. Moreover, with the increasing attention paid to the influence of genetic and environmental factors on public health, it has become an important direction to study the role of these two types of factors in inflammatory and aging related diseases.
It is well known that genetics is closely related to biological individuals; therefore, the discovery of relevant susceptibility genes can help identify high-risk populations, establish their biological detection indicators and evaluation systems, and provide a solid foundation for intervention in inflammatory and aging diseases. In addition, environmental factors have been affecting human health directly or indirectly. Thus, it is important to investigate environmental risk factors for inflammation and aging related diseases, and to explore possible gene-environment interactions effects to establish comprehensive prevention strategies.
This Research Topic aims to explore the potential risk factors for the development of inflammation and aging related diseases, including discovering new susceptibility genes, exploring the influence and intervention of environmental factors (such as air pollution and meteorological factors, etc.) on inflammation and aging related diseases, as well as the influence of gene-environment interaction on inflammation and aging related diseases. Meanwhile, we welcome articles which seeks to identify the disease burden of inflammation and aging-related diseases. In addition, public health policies that address the prevention and treatment of inflammation and aging related diseases for population health based on genetic and environmental factors are encouraged, as well as new ideas on the etiology and intervention of inflammation and aging related diseases.
- Exploration of potential susceptibility genes related to inflammation and aging related diseases.
- Association between environmental factors with inflammation and aging related diseases.
- Influence of gene-environment interactions on the development of inflammation and aging related diseases.
- Identification of the disease burden of inflammation and aging-related diseases. Interventions for environmental influences on inflammation and aging related diseases.
- Prevention and control strategies based on the role of genetics and environment in inflammation and aging related diseases.
It is estimated that by 2050, more than 20% of the world's population will be over 60 years old, which could impose a huge economic, medical and financial burden on society. With the increase of age, there is a progressive increase of proinflammatory response state in the body. During the aging process, this defensive inflammatory response may overreact, leading to damage the body and thus to various diseases such as osteoporosis, rheumatoid arthritis, osteoarthritis, and sarcopenia. However, the pathogenesis of inflammation and aging related diseases remains unclear, and it is generally believed that it may be the result of a combination of genetic, environmental and immune abnormalities. Among these factors, the impact of immune abnormalities in these diseases has been widely and deeply discussed. Moreover, with the increasing attention paid to the influence of genetic and environmental factors on public health, it has become an important direction to study the role of these two types of factors in inflammatory and aging related diseases.
It is well known that genetics is closely related to biological individuals; therefore, the discovery of relevant susceptibility genes can help identify high-risk populations, establish their biological detection indicators and evaluation systems, and provide a solid foundation for intervention in inflammatory and aging diseases. In addition, environmental factors have been affecting human health directly or indirectly. Thus, it is important to investigate environmental risk factors for inflammation and aging related diseases, and to explore possible gene-environment interactions effects to establish comprehensive prevention strategies.
This Research Topic aims to explore the potential risk factors for the development of inflammation and aging related diseases, including discovering new susceptibility genes, exploring the influence and intervention of environmental factors (such as air pollution and meteorological factors, etc.) on inflammation and aging related diseases, as well as the influence of gene-environment interaction on inflammation and aging related diseases. Meanwhile, we welcome articles which seeks to identify the disease burden of inflammation and aging-related diseases. In addition, public health policies that address the prevention and treatment of inflammation and aging related diseases for population health based on genetic and environmental factors are encouraged, as well as new ideas on the etiology and intervention of inflammation and aging related diseases.
- Exploration of potential susceptibility genes related to inflammation and aging related diseases.
- Association between environmental factors with inflammation and aging related diseases.
- Influence of gene-environment interactions on the development of inflammation and aging related diseases.
- Identification of the disease burden of inflammation and aging-related diseases. Interventions for environmental influences on inflammation and aging related diseases.
- Prevention and control strategies based on the role of genetics and environment in inflammation and aging related diseases.
