About this Research Topic
The contributions from the neuro-psycho-immunology field were aggregated and intensely discussed at the 13th PIE meeting in March 2016 and have broad interest to the wider psychiatric community, representing a ‘hot topic’ in psychiatric research, currently in its infancy. Several themes will be presented to outline the state of knowledge in this area as a Research Topic at Frontiers. They will include the status of knowledge and open questions regarding the neuroinflammatory contribution to psychiatric disease, presented as a selection of reviews and original work as discussed at the 13th PIE meeting.
These will focus on the important themes relevant to the patients’ perspective and assess how frequently autoimmune encephalitis is diagnosed and treated according to newly established diagnostic and therapeutic possibilities, which might lead to full recovery. Pioneers of these aspects will guide this section, including Dr. Najjar and others. Included will be novel data from a nationwide survey in Denmark, critically assessing the present practice guidelines, which will also address the apparent diagnostic gap. The prevalence of misdiagnosis and attitudes to diagnostic procedures, as well as propose up-to-date approaches will also be examined. A discussion of the present diagnostic options and needed further improvements including imaging, CSF analysis, and neurophysiological methods will be presented. Further reviews of therapeutic options will be presented and potential therapeutic pathways proposed, discussing emerging PIE research in an interdisciplinary framework from basic sciences to clinic. These reviews will also address ethical issues of extraordinary importance in the context of psychiatric illness and potential biological causation. In context with the 13th PIE meeting and in preparation of the next meeting ( idea is getting funded for the 14th PIE meeting by hopefully winning the grant from Frontiers with this Research Topic ) we encourage all participants of the 13th PIE meeting to submit papers of any type (see guidelines).
Keywords: Psycho-Neuro-Immunology, Autoimmunencephalitis, Autoimmune-Encephalopathy, Mild Encephalitis, Etiopathology, Schizophrenia, Bipolar disorder, Affective disorder
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.