The scar is the general term for the appearance, morphology, and histopathological changes of normal skin tissue caused by trauma, burns, surgery, etc. And it is the inevitable result of the process of wound healing. Scars may lead to physical functional problems and emotional disturbances that severely decrease the patient's quality of life. Due to the unelucidated mechanisms underlying scar, however, discussion on the effectiveness of existing preventive and therapeutic strategies remains limited.
Wound healing is a complex and fragile process accompanied by hemostasis, inflammation, proliferation, and remodeling. Any abnormality in each process may lead to delayed wound healing and/or obvious scar. The current therapies for treating scars, including surgical and non-surgical methods, have limitations. Therapeutic interventions targeting skin regeneration are recently considered promising approaches for scar management in the generation of human skin organoids, multifunctional wound dressing etc. But more research is needed before they are translated into clinical practice. Thus, it is urgent to explore the biology of scars and seek more effective prevention and treatment strategies to improve wound healing and promote skin regeneration.
This topic aims to explore both basic and clinical research on the latest scar research progress at the different stages of scar formation (hemostasis, inflammation, proliferation, remodeling), using transcriptomics, metabolomics, proteomics, and other multi-omics technologies, so as to have a more comprehensive and in-depth understanding of scar formation, skin regeneration, and the progress for scar-free healing.
We welcome the following topics, but are not limited to:
- The latest research on the mechanism of scar formation
- The latest research, clinical trials or clinical case reports on scar treatment
- Potential therapeutic markers for scar
- Research and application of various topical anti-scarring agents in scar
- The latest research of scar formation and skin regeneration on stem cells and other related therapies
- Scar-free wound healings
The scar is the general term for the appearance, morphology, and histopathological changes of normal skin tissue caused by trauma, burns, surgery, etc. And it is the inevitable result of the process of wound healing. Scars may lead to physical functional problems and emotional disturbances that severely decrease the patient's quality of life. Due to the unelucidated mechanisms underlying scar, however, discussion on the effectiveness of existing preventive and therapeutic strategies remains limited.
Wound healing is a complex and fragile process accompanied by hemostasis, inflammation, proliferation, and remodeling. Any abnormality in each process may lead to delayed wound healing and/or obvious scar. The current therapies for treating scars, including surgical and non-surgical methods, have limitations. Therapeutic interventions targeting skin regeneration are recently considered promising approaches for scar management in the generation of human skin organoids, multifunctional wound dressing etc. But more research is needed before they are translated into clinical practice. Thus, it is urgent to explore the biology of scars and seek more effective prevention and treatment strategies to improve wound healing and promote skin regeneration.
This topic aims to explore both basic and clinical research on the latest scar research progress at the different stages of scar formation (hemostasis, inflammation, proliferation, remodeling), using transcriptomics, metabolomics, proteomics, and other multi-omics technologies, so as to have a more comprehensive and in-depth understanding of scar formation, skin regeneration, and the progress for scar-free healing.
We welcome the following topics, but are not limited to:
- The latest research on the mechanism of scar formation
- The latest research, clinical trials or clinical case reports on scar treatment
- Potential therapeutic markers for scar
- Research and application of various topical anti-scarring agents in scar
- The latest research of scar formation and skin regeneration on stem cells and other related therapies
- Scar-free wound healings
