There are two basic purposes for absorbing nutrients. One is to support life. Another is to defend against infection. Thus, nutrition metabolism and immune inflammation are closely intertwined and very relevant.
In the process of supporting life and fighting infection, immune cells constantly change and adjust their status, playing the immune roles of defense, surveillance, and self-homeostasis effectively. This process often needs the metabolic system to make corresponding changes to provide energy and basic nutrients to immune cells. Meanwhile, how the metabolic system changes also affect how important the role immune cells play and the way that they respond. Metabolism and immunity are basic needs for the survival of the organism. During the long human evolutionary process on earth, we developed shared pathways for metabolic and immune responses. Thus, the immune response and metabolic regulation are highly integrated and functionally interdependent. As a result, the immune system and basic metabolic organization are relevant as a whole and jointly influence the body's various activities. The complex and bound interaction between metabolism and immunity can somewhat be considered a core mechanism of the human body’s homeostasis regulation.
The goal of this Research Topic is to provide a platform for discussing the role of metabolic regulation in infectious diseases caused by microbes. It also aims to identify how main targets coordinate the human metabolism and immunity systems, in the context of the global epidemic of infectious disease.
We welcome high-quality Original Research and Review papers addressing this topic. Possible research themes include but are not limited to:
(1) Physiological and pathophysiological roles of metabolism in microbial infection process;
(2) Development of inhibitors and functional metabolites for diagnostics and therapeutics;
(3) Mechanisms of metabolic regulation in immune defense against microbiomes;
(4) Metabolomics research in immune defense against microbiomes;
(5) Analytical methods for effective metabolite screening in the microbial infection process.
There are two basic purposes for absorbing nutrients. One is to support life. Another is to defend against infection. Thus, nutrition metabolism and immune inflammation are closely intertwined and very relevant.
In the process of supporting life and fighting infection, immune cells constantly change and adjust their status, playing the immune roles of defense, surveillance, and self-homeostasis effectively. This process often needs the metabolic system to make corresponding changes to provide energy and basic nutrients to immune cells. Meanwhile, how the metabolic system changes also affect how important the role immune cells play and the way that they respond. Metabolism and immunity are basic needs for the survival of the organism. During the long human evolutionary process on earth, we developed shared pathways for metabolic and immune responses. Thus, the immune response and metabolic regulation are highly integrated and functionally interdependent. As a result, the immune system and basic metabolic organization are relevant as a whole and jointly influence the body's various activities. The complex and bound interaction between metabolism and immunity can somewhat be considered a core mechanism of the human body’s homeostasis regulation.
The goal of this Research Topic is to provide a platform for discussing the role of metabolic regulation in infectious diseases caused by microbes. It also aims to identify how main targets coordinate the human metabolism and immunity systems, in the context of the global epidemic of infectious disease.
We welcome high-quality Original Research and Review papers addressing this topic. Possible research themes include but are not limited to:
(1) Physiological and pathophysiological roles of metabolism in microbial infection process;
(2) Development of inhibitors and functional metabolites for diagnostics and therapeutics;
(3) Mechanisms of metabolic regulation in immune defense against microbiomes;
(4) Metabolomics research in immune defense against microbiomes;
(5) Analytical methods for effective metabolite screening in the microbial infection process.
