About this Research Topic
The goal of this Research Topic is to identify potential impediments to the delivery of immuno-modulatory anti-cancer agents at the molecular level. We also welcome research on the assessment of the feasibility of overcoming such barriers, potential successful delivery mechanisms or further challenges associated with these.
We welcome original research including animal studies and/or strong in vitro evidence, and review articles, including, but not limited to, the following Topics within the theme of cancer:
- Assessment of potential barriers to drug delivery
- Challenges to delivery of drugs or drug formulations
- Synthetic or naturally occurring immune modulators
- Effect of drug combinations on downstream immune activity
- Drugs or drug formulations can include and are not limited to:
- Nanocarriers including liposomes, polymer nanoparticles, polymer-lipid hybrid nanoparticles
- Drug-carrier conjugates
- Lipoplexes for delivery of nucleic acids
- Novel chemical moieties
- Analysis of drugs: anti-cancer immuno-modulatory agents and/or combinations. Drugs can be of chemical or biological origin, novel or established
- Analysis of nanoparticulate- and gene-based therapies, and downstream immune responses are also welcome
Keywords: Immunotherapy, Resistance, Tumor Microenvironment, Anti-Cancer Drugs, Immune Checkpoint Inhibitors
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.