Research Topic

Stroke in Elderly: Current Status and Future Directions

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Elderly population is growing rapidly worldwide. The incidence of stroke doubles in octogenarians. In the USA the number of people aged >85 years, who currently constitute 2% of the total population will double by 2060. The very elderly population is growing rapidly worldwide. This growth of the aging ...

Elderly population is growing rapidly worldwide. The incidence of stroke doubles in octogenarians. In the USA the number of people aged >85 years, who currently constitute 2% of the total population will double by 2060. The very elderly population is growing rapidly worldwide. This growth of the aging population combined with their higher incidence of stroke is expected to significantly increase.

It is therefore important for physicians to understand the etiologies of stroke in this population, minimize risk factors for stroke, manage acute stroke in effective manner and focus on rehabilitation. In this Research Topic, we would like to focus on the following topics but other topics pertaining to elderly stroke are also welcome:

Prevention: Stroke prevention is major issue in elderly due to the high incidence. Articles in this topic should focus on blood pressure goals, anticoagulation practices, asymptomatic carotid disease, statin use etc. in elderly patients.

Micro-hemorrhages and Intracerebral Hemorrhage: The presence of micro-hemorrhages predisposes elderly to intracerebral hemorrhage. Articles for this topic should evaluate the risk attributed to micro-hemorrhages, treatment decisions pertaining to antiplatelet and anticoagulant use, tissue plasminogen use in patients with micro-hemorrhages etc.

Carotid endarterectomy (CEA) and Carotid artery stenting (CAS): The long term risk of carotid artery stenosis needs to further studied in elderly stroke patients and manuscripts focusing on this topic should address the utility of CEA, CAS and aggressive medical therapy for carotid artery disease both symptomatic and asymptomatic.

Use of tissue plasminogen activator tPA and mechanical Thrombectomy: Management of acute ischemic stroke in elderly needs to be further evaluated specially in the context of recanalization therapies and their impact on long term outcomes.

Hemicraniectomy for malignant ischemic stroke: Articles should focus on role of hemicraniectomy in elderly patients with malignant cerebral edema due to territorial ischemic stroke in preventing death and disability.

Stroke recovery and rehab: The potential for recovery in elderly patients after stroke, specialized therapy modalities focusing on elderly and impact on outcomes should be the focus of manuscripts.


Keywords: ischemic stroke, octogenarians, nonagenarians, carotid stenosis, tPA, mechanical thrombectomy, micro-hemorrhages, rehabilitation


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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