About this Research Topic
It is estimated that 1 in 10 people suffer from thyroid disease; and in women, it was found that at least 1 in 8 will develop a thyroid disease at some point in their lifetime. Symptoms of thyroid disease can often vary from person to person or be non-specific. It is estimated that 50% of thyroid disorders are undiagnosed or misdiagnosed. Patients and clinicians can attribute symptoms of thyroid disease to depression, obesity, menopause, stress, eating disorders, or other diseases or environmental factors. Considering these statistics, this Research Topic will be used as a platform to shine a light on the latest neuroscience-based research.
Hormones produced by the thyroid are important during early brain development as well as in maintaining brain health and function throughout the lifetime. These hormones can regulate neuronal and glial mechanisms, neurogenesis, differentiation, synaptogenesis, and myelination and thyroid hormone deficiencies can lead to many psychological disorders, neurological impairment, and intellectual deficits. Dysregulated hormone levels also impair everyday cognitive functions such as attention, memory, perceptual function, motor function, alertness, and more.
This Research Topic aims to address the Neuro-specific dimensions of this UN day. Topics may include but are by no means limited to:
- Mechanisms of thyroid hormones actions in the adult brain
- Mechanisms and symptomology of impaired cognitive function in thyroid disease
- Brain pathophysiology in thyroid disease
- Thyroid hormone processes associated with aging
- Pathogenesis of brain disorders in thyroid disease
- Thyroid hormones action in the developing brain
- Thyroid hormones as the target for treatment and prevention interventions.
- Thyroid hormone imbalances in patients receiving checkpoint inhibitor therapies for cancer.
- CNS metastases from thyroid cancer.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.