Research Topic

Bone: Organic/Inorganic Matter Architecture and Mechanics

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At a molecular level, bone constitutes of mineral and protein components. The mineral phase plays a significant role, mainly because it strongly affects bone’s strength and quality. Spectroscopy, microtomography, X-ray absorptiometry are some techniques to study the bone mineral component.
The organic ...

At a molecular level, bone constitutes of mineral and protein components. The mineral phase plays a significant role, mainly because it strongly affects bone’s strength and quality. Spectroscopy, microtomography, X-ray absorptiometry are some techniques to study the bone mineral component.
The organic phase of bone is composed mostly of collagen. Bone collagen structure in normal and pathological tissues can be illustrated using microscopic techniques and image processing of optical data.

With aging, bone deteriorates, leading to a variety of serious clinical problems. The overall socioeconomic benefit derived from early diagnosis and prevention of bone disorders is important because it improves the quality of life and minimizes the cost of treating the severe disabilities caused by these diseases. Since a great number of people are susceptible to bone disorders, effective diagnostic techniques and prevention are crucial.

In modern populations, osteoporotic fractures are becoming increasingly common, with the wrist, spine and hip being the primary sites. Fracture is an inherently mechanical event indicating the load-bearing capacity of a particular skeletal element. Implantation of orthopedic prostheses for conditions such as osteoarthritis require a strong bone for optimal fixation, a difficult requirement for sites such as the aged spine or hip, where bone strength can be greatly compromised. Updated information on biomechanical analyses of whole bone and bone-implant systems can offer a significant input.

This Research Topic will cover any developments and applications of bone structure and properties in the field of biomedical physics. Also, we encourage authors to share their experiences in related research topics.


Keywords: Bone structure, bone mineral, bone collagen, bone properties, bone mechanics


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