Research on the mechanisms of viral transformation and oncogenesis has laid the foundation for our current understanding of certain cancers. For instance, some oncogenes are activated or taken over by retroviruses, and some viral proteins impair tumor suppressor gene functions. Particular viruses from multiple virus families, as well as unusual or unclassified viruses, have been implicated in causing cancers through natural occurrence or experimentation on animals. It is believed that 15% to 20% of all human cancer cases are linked to infections by one of seven viruses: Epstein-Barr virus, hepatitis B virus, hepatitis C virus, human herpesvirus 8, human T-cell lymphotropic virus type 1, human papillomaviruses, and Merkel cell polyomavirus.
This Research Topic focuses on oncogenic viruses and the features of their transforming interactions with host cells. We are interested in submissions that deal with tumor biology, the molecular mechanisms operated by viral proteins during the oncogenesis, and the immunology of tumor viruses. We also welcome the identification and confirmation of novel tumor viruses.
We look forward to the submission of Original Research, Review and Mini Review, Opinion, Hypothesis & Theory, Methods, Technology and Code, and Perspective, on but not limited to the following topics:
• Basic research that furthers our understanding of the mechanisms underlying how viruses stimulate or evade the immune response, and infection in tumorigenesis as well as molecular mechanisms of drug resistance.
• Translational research that focuses on identifying new drugs and new approaches for developing diagnostic and therapeutic modalities for viral infections and cancer.
• Clinical studies informing diagnosis, treatment, and vaccine prevention for viral infection and related cancer diseases.
• Other innovative studies related to viruses and tumors.
Research on the mechanisms of viral transformation and oncogenesis has laid the foundation for our current understanding of certain cancers. For instance, some oncogenes are activated or taken over by retroviruses, and some viral proteins impair tumor suppressor gene functions. Particular viruses from multiple virus families, as well as unusual or unclassified viruses, have been implicated in causing cancers through natural occurrence or experimentation on animals. It is believed that 15% to 20% of all human cancer cases are linked to infections by one of seven viruses: Epstein-Barr virus, hepatitis B virus, hepatitis C virus, human herpesvirus 8, human T-cell lymphotropic virus type 1, human papillomaviruses, and Merkel cell polyomavirus.
This Research Topic focuses on oncogenic viruses and the features of their transforming interactions with host cells. We are interested in submissions that deal with tumor biology, the molecular mechanisms operated by viral proteins during the oncogenesis, and the immunology of tumor viruses. We also welcome the identification and confirmation of novel tumor viruses.
We look forward to the submission of Original Research, Review and Mini Review, Opinion, Hypothesis & Theory, Methods, Technology and Code, and Perspective, on but not limited to the following topics:
• Basic research that furthers our understanding of the mechanisms underlying how viruses stimulate or evade the immune response, and infection in tumorigenesis as well as molecular mechanisms of drug resistance.
• Translational research that focuses on identifying new drugs and new approaches for developing diagnostic and therapeutic modalities for viral infections and cancer.
• Clinical studies informing diagnosis, treatment, and vaccine prevention for viral infection and related cancer diseases.
• Other innovative studies related to viruses and tumors.
