About this Research Topic
Although the mechanisms behind salt adaptation of haloarchaea at molecular, cellular, metabolic, and physiological levels have raised much interest, they are still far from being completely understood. The continuing interest in haloarchaea has driven the development of molecular genetic tools, functional genomics and proteomics, and imaging protocols. Given the current known abundance of diversity of haloarchaea and the complex adaptive mechanisms, the application of genetics, ‘omics’ strategies, and advanced microscopy techniques in haloarchaea will help to comprehensively investigate the molecular and physiological mechanisms of adaptation in response to environmental stimuli or perturbations and thereby advance the understanding on haloarchaeal biology and physiology.
This Research Topic welcomes Original Research, Methods, Review, Mini Review, Perspectives, Hypothesis and Theory, and Technology and Code articles on the following, but not limited to, subtopics:
• The development of genetic tools of haloarchaea, including new genetic markers, shuttle/cloning vectors, reporter genes and promoters, and efficient gene manipulation systems (genome scale mutant libraries, CRISPR-Cas mediated genome editing etc).
• The application of “omics” technologies (including genomics, proteomics, transcriptomics, metabolomics) to investigate DNA replication and repair, transcription machinery, protein synthesis and adaptation, metabolic pathways.
• Using advanced imaging techniques to study the cell morphology and structural dynamics of haloarchaea and provide new knowledge about how haloarchaeal cells organise their internal cellular components in space and time.
• Biotechnological applications of haloarchaea.
Keywords: Haloarchaea, Genetics, Omics technologies, Cell Shape, Structural dynamics
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.