The unique properties and potential benefits of nanobiomaterials (NBMs) have captured the attention of biomedical engineering. Given that most organs and tissues are nanostructured, mimicking the structure and features of NBMs has emerged as a promising area of research. NBMs offer several advantages, including high-loading ability, improved mechanical properties, and optical, electrical, magnetic, and antibacterial characteristics. However, their clinical applications are still in the early stages, as their toxicity and biocompatibility require investigation. Due to their physicochemical properties, NBMs have the potential to cross biological barriers and deposit in various regions of the human body, which may result in adverse effects. Although NBMs may promote cell adhesion and tissue regeneration, it is necessary to test them for immunotoxicity, oxidative stress, and genotoxicity to ensure their safety. Current research trends are focused on assessing the in vitro and in vivo toxicity and biocompatibility of NBMs and defining and characterizing certified standards for standardized test protocols.
The central theme of this research topic is the examination of the interaction between NBMs and cells/tissues, with a particular focus on how size, morphology, shape, and surface impact their toxicity, biocompatibility, and immunogenicity. The ultimate objective is to generate innovative concepts for diverse biomedical applications. The issue offers an overview of the distinct properties of NBMs, their assessment for biocompatibility and toxicity, as well as future prospects. The content includes successful models of NBMs, such as nanomaterials-integrated NBMs. We encourage submissions of Original Research, Review, Mini Review, and Perspective articles on a range of themes related to this research topic, including but not limited to:
• Evaluation of the biocompatibility of NBMs
• Engineering multifunctional NBMs for biomedical applications, and nanomedicine
• NBMs-based drug delivery strategies
• Engineering in vitro NBMs-based models to study cell-NBMs interactions
The unique properties and potential benefits of nanobiomaterials (NBMs) have captured the attention of biomedical engineering. Given that most organs and tissues are nanostructured, mimicking the structure and features of NBMs has emerged as a promising area of research. NBMs offer several advantages, including high-loading ability, improved mechanical properties, and optical, electrical, magnetic, and antibacterial characteristics. However, their clinical applications are still in the early stages, as their toxicity and biocompatibility require investigation. Due to their physicochemical properties, NBMs have the potential to cross biological barriers and deposit in various regions of the human body, which may result in adverse effects. Although NBMs may promote cell adhesion and tissue regeneration, it is necessary to test them for immunotoxicity, oxidative stress, and genotoxicity to ensure their safety. Current research trends are focused on assessing the in vitro and in vivo toxicity and biocompatibility of NBMs and defining and characterizing certified standards for standardized test protocols.
The central theme of this research topic is the examination of the interaction between NBMs and cells/tissues, with a particular focus on how size, morphology, shape, and surface impact their toxicity, biocompatibility, and immunogenicity. The ultimate objective is to generate innovative concepts for diverse biomedical applications. The issue offers an overview of the distinct properties of NBMs, their assessment for biocompatibility and toxicity, as well as future prospects. The content includes successful models of NBMs, such as nanomaterials-integrated NBMs. We encourage submissions of Original Research, Review, Mini Review, and Perspective articles on a range of themes related to this research topic, including but not limited to:
• Evaluation of the biocompatibility of NBMs
• Engineering multifunctional NBMs for biomedical applications, and nanomedicine
• NBMs-based drug delivery strategies
• Engineering in vitro NBMs-based models to study cell-NBMs interactions
