About this Research Topic
Although inflammation is virtually present in any chronic disease, whether this response is the outcome of other processes that drive the disease or, instead, being itself a mechanism that promotes cell and tissue damage, is an effector of the disease process remains to be fully elucidated. Understanding the role of inflammation in each of those diseases is thus crucial to determine its value as a therapeutic target “latu sensu” and more precisely to identify specific components, from DAMPs, miRNAs, cytokines and their receptors to signaling pathways, and cellular processes whose modulation can be effective in preventing, treating and curing each of those diseases. This research topic aims at bringing together current knowledge on critical processes for cell homeostasis that are reciprocally modulated and/or impaired by inflammation and that are affected in and contribute to disease and so, welcomes original articles and focused reviews that tackle these subjects, either from a basic research or clinical point of view.
Keywords: Chronic diseases, inflammation, metabolic alterations, pro-inflammatory signaling pathways
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