Unconventional Myosins in Motile and Contractile Functions: Fifty Years on the Stage

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Editorial

12 June 2024

Editorial: Unconventional myosins in motile and contractile functions: fifty years on the stage

Manuel H. Taft

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Maria Jolanta Redowicz

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Maria Jolanta Redowicz

Laboratory of Molecular Basis of Cell Motility, Nencki Institute of Experimental Biology, Polish Academy of Sciences

Manuel H. Taft

Hannover Medical School

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Myosins, actin-dependent molecular motors, are best known for their involvement in muscle contraction. However, besides classical (conventional) myosins, there is a vast number of other myosin motors that structurally and functionally do not resemble muscle myosins and therefore are termed as unconventional myosins. Since discovery in 1973 of the first unconventional myosin, myosin I, in Acanthamoeba castellanii by Thomas D. Pollard and Edward D. Korn, it has been shown that unconventional myosins form a large family, members of which are involved in a plethora of cellular functions, including those associated with intracellular trafficking and cell migration. However, despite the intensive research still many questions persist about their specific role(s) in these processes.

This Frontiers Research Topic aims at presenting the latest research and hypotheses on the role(s) of unconventional myosins in motile and contractile functions.

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Editors

Maria Jolanta Redowicz

Laboratory of Molecular Basis of Cell Motility, Nencki Institute of Experimental Biology, Polish Academy of Sciences

Manuel H. Taft

Hannover Medical School

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Frontiers in Physiology

Striated Muscle Physiology, Cell Physiology

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