Excess adiposity and insulin resistance are the pathogenic core of type 2 diabetes mellitus (T2DM) and steatotic liver disease (SLD). Since T2DM is a risk factor for SLD progression, and SLD is associated with higher cardiovascular disease in T2DM, both diseases negatively influence each other. The spectrum of SLD ranges from steatosis to steatohepatitis or cirrhosis in advanced cases. It is, therefore, crucial to diagnose and treat both chronic diseases as early as possible. Risk profiling, novel biomarkers for predicting the progression of SLD, and advances in treatments are some of the most captivating areas of research.
The goal of this Research Topic is to update the latest information related to medical and nutritional intervention, supplements, risk profiling, biomarkers, and novel treatments in patients with T2DM and SLD.
Specific themes of interest include but are not limited to:
• Nutritional interventions for SLD and T2DM
• The use of antioxidants for SLD and T2DM
• The use of probiotics for SLD and T2DM
• Incretin-based therapies for SLD and T2DM
• SGLT2 inhibitors and SLD
• Risk profiling of SLD and T2DM
• Novel biomarkers of SLD and T2DM
• Diagnosis of SLD and T2DM
Excess adiposity and insulin resistance are the pathogenic core of type 2 diabetes mellitus (T2DM) and steatotic liver disease (SLD). Since T2DM is a risk factor for SLD progression, and SLD is associated with higher cardiovascular disease in T2DM, both diseases negatively influence each other. The spectrum of SLD ranges from steatosis to steatohepatitis or cirrhosis in advanced cases. It is, therefore, crucial to diagnose and treat both chronic diseases as early as possible. Risk profiling, novel biomarkers for predicting the progression of SLD, and advances in treatments are some of the most captivating areas of research.
The goal of this Research Topic is to update the latest information related to medical and nutritional intervention, supplements, risk profiling, biomarkers, and novel treatments in patients with T2DM and SLD.
Specific themes of interest include but are not limited to:
• Nutritional interventions for SLD and T2DM
• The use of antioxidants for SLD and T2DM
• The use of probiotics for SLD and T2DM
• Incretin-based therapies for SLD and T2DM
• SGLT2 inhibitors and SLD
• Risk profiling of SLD and T2DM
• Novel biomarkers of SLD and T2DM
• Diagnosis of SLD and T2DM