The link between the microbiome and head and neck cancers is an emerging field of study. It has been observed that alterations in the oral and gut microbiome can contribute to the development and progression of these cancers.
One way in which the microbiome affects head and neck cancers is through chronic inflammation. Certain bacteria that reside in the oral cavity can promote inflammation, which creates an environment conducive to cancer development. Inflammation can also weaken the immune system’s ability to detect and eliminate cancer cells. In addition, some specific strains of bacteria have been found to produce carcinogenic compounds or alter the metabolism of certain substances, potentially increasing the risk of head and neck cancers. Furthermore, the microbiome can influence the efficacy and side effects of cancer treatments such as chemotherapy and immunotherapy.
This Research Topic aims to explore the complex relationship between the microbiome and head and neck cancers, with a focus on experimental studies. In particular, we encourage the submissions of high-quality manuscripts reporting original research related to the investigation of the role of microbiome in the context of the disease, including the identification of specific microbial biomarkers and their functional roles, and their potential use as a diagnostic tool. Also, we are interested in research that explores the impact of the microbiome on cancer therapy outcomes, as well as exploring the interaction between the microbiome and the immune system in the context of head and neck cancer.
Please note, manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
Keywords:
microbiome, head and neck cancer, biomarkers, diagnostics, therapeutics, carcinogenesis
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
The link between the microbiome and head and neck cancers is an emerging field of study. It has been observed that alterations in the oral and gut microbiome can contribute to the development and progression of these cancers.
One way in which the microbiome affects head and neck cancers is through chronic inflammation. Certain bacteria that reside in the oral cavity can promote inflammation, which creates an environment conducive to cancer development. Inflammation can also weaken the immune system’s ability to detect and eliminate cancer cells. In addition, some specific strains of bacteria have been found to produce carcinogenic compounds or alter the metabolism of certain substances, potentially increasing the risk of head and neck cancers. Furthermore, the microbiome can influence the efficacy and side effects of cancer treatments such as chemotherapy and immunotherapy.
This Research Topic aims to explore the complex relationship between the microbiome and head and neck cancers, with a focus on experimental studies. In particular, we encourage the submissions of high-quality manuscripts reporting original research related to the investigation of the role of microbiome in the context of the disease, including the identification of specific microbial biomarkers and their functional roles, and their potential use as a diagnostic tool. Also, we are interested in research that explores the impact of the microbiome on cancer therapy outcomes, as well as exploring the interaction between the microbiome and the immune system in the context of head and neck cancer.
Please note, manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
Keywords:
microbiome, head and neck cancer, biomarkers, diagnostics, therapeutics, carcinogenesis
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.