About this Research Topic
The prevalence of obesity is rapidly increasing nowadays, which has become an important clinical and public health burden worldwide. As a complex disease characterized by abnormal or excessive fat accumulation, obesity may amplify the likelihood of various diseases and health-related issues, such as metabolic diseases, cardiovascular diseases, cognitive dysfunction, cancers, etc.
Exercise has been suggested to be a modifiable lifestyle factor to prevent or treat obesity. However, it is still unclear which specific type of exercise may have a more significant effect on obesity. More studies are still needed to investigate the optimal exercise mode, intensity, and frequency, as well as to explore the potential mechanisms that underline the changes in obesity. Besides exercise, diet is another important factor that may affect obesity. Up till now, however, the combined effects of different exercise protocols and dietary strategies on obesity remain unclear. Furthermore, growing evidence has shown that exercise can increase the release of cytokines, including irisin, IL-6, and ANGPTL4, from skeletal muscle or other organs into the blood. These cytokines can modulate adipose tissue metabolism. However, there is still much to explore to fully understand the roles of exercise-induced cytokines and the underlying mechanisms involved, especially in relation to the treatment and prevention of obesity.
Therefore, in this Research Topic, we welcome submissions from authors working in different research areas, including exercise, nutrition, and obesity, to advance the knowledge and the practical implications in this field. Submissions using animal and human models are also welcome. Both original research and review articles will be considered for publication.
Some potential themes of interest for this Research Topic include, but are not limited to:
• The potential mechanisms behind the benefits of exercise or dietary intervention on preventing and treating obesity
• The combined effects of exercise and dietary interventions on preventing and treating obesity and the underlying mechanisms
• The roles of exercise-induced cytokines in regulating adipose tissue metabolism and underlying mechanisms.
Exercise has been suggested to be a modifiable lifestyle factor to prevent or treat obesity. However, it is still unclear which specific type of exercise may have a more significant effect on obesity. More studies are still needed to investigate the optimal exercise mode, intensity, and frequency, as well as to explore the potential mechanisms that underline the changes in obesity. Besides exercise, diet is another important factor that may affect obesity. Up till now, however, the combined effects of different exercise protocols and dietary strategies on obesity remain unclear. Furthermore, growing evidence has shown that exercise can increase the release of cytokines, including irisin, IL-6, and ANGPTL4, from skeletal muscle or other organs into the blood. These cytokines can modulate adipose tissue metabolism. However, there is still much to explore to fully understand the roles of exercise-induced cytokines and the underlying mechanisms involved, especially in relation to the treatment and prevention of obesity.
Therefore, in this Research Topic, we welcome submissions from authors working in different research areas, including exercise, nutrition, and obesity, to advance the knowledge and the practical implications in this field. Submissions using animal and human models are also welcome. Both original research and review articles will be considered for publication.
Some potential themes of interest for this Research Topic include, but are not limited to:
• The potential mechanisms behind the benefits of exercise or dietary intervention on preventing and treating obesity
• The combined effects of exercise and dietary interventions on preventing and treating obesity and the underlying mechanisms
• The roles of exercise-induced cytokines in regulating adipose tissue metabolism and underlying mechanisms.
Keywords: Exercise, Diet, Obesity, Cytokines
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
