Environmental challenges and endocrine dysregulation have become a focal point in contemporary biomedical research due to their profound implications on human health. Recent studies have highlighted the significant role of environmental stress factors, such as air pollution, climate change, and exposure to heavy metals and emerging contaminants, in the development of various human diseases. Epidemiological and animal model research has consistently demonstrated a link between air pollutants, particularly those from combustion sources like PM2.5, benzene, and ozone, and increased mortality and morbidity related to endocrine disorders, including cardiometabolic diseases. These environmental challenges often act as endocrine disruptors, interfering with hormone synthesis, secretion, transportation, and function. Despite substantial progress in understanding these effects and mechanisms, there remains a critical need to further explore the association, mechanisms, and interventions related to environment-induced endocrine dysregulation to enhance biomedical and public health research communication.This Research Topic aims to delve deeper into the intricate relationship between environmental challenges and endocrine dysregulation. The primary objectives include investigating the adverse effects of environmental stressors on endocrine health, elucidating the mechanistic links between these stressors and endocrine-related diseases, and exploring potential interventions. Key questions to be addressed include how environmental factors predispose individuals to endocrine diseases, the role of hormonal responses in modulating endocrine functions under stress, and the interactions between genetic, environmental, and psychiatric factors in these diseases.To gather further insights into the complex interplay between environmental challenges and endocrine dysregulation, we welcome Original Research and Review articles addressing, but not limited to, the following themes:- Adverse effects of air pollution, climate change, and endocrine-disrupting chemicals on predisposition to endocrine diseases- Hormonal- or transmitter-mediated stress responses to environmental challenges that modulate endocrine and metabolic functions- Mechanistic links or mechanistic basis for environmental stressors, endocrine dysregulation, and cardiometabolic diseases- Interactions between genetic, environmental, and psychiatric factors in endocrine diseases- Interventions, including both traditional and modern medicine, on endocrine-related diseases induced by environmental challenges- The role of endocrine disruption triggered by environmental factors in developmental, reproductive, neurological, cardiovascular, and metabolic disorders.Special Note for Authors:To effectively advance our understanding of environmental challenges and endocrine dysfunction, we highly encourage authors to review the previous Research Topic, ““Environmental Stressors and Metabolic Disease”.
Environmental challenges and endocrine dysregulation have become a focal point in contemporary biomedical research due to their profound implications on human health. Recent studies have highlighted the significant role of environmental stress factors, such as air pollution, climate change, and exposure to heavy metals and emerging contaminants, in the development of various human diseases. Epidemiological and animal model research has consistently demonstrated a link between air pollutants, particularly those from combustion sources like PM2.5, benzene, and ozone, and increased mortality and morbidity related to endocrine disorders, including cardiometabolic diseases. These environmental challenges often act as endocrine disruptors, interfering with hormone synthesis, secretion, transportation, and function. Despite substantial progress in understanding these effects and mechanisms, there remains a critical need to further explore the association, mechanisms, and interventions related to environment-induced endocrine dysregulation to enhance biomedical and public health research communication.This Research Topic aims to delve deeper into the intricate relationship between environmental challenges and endocrine dysregulation. The primary objectives include investigating the adverse effects of environmental stressors on endocrine health, elucidating the mechanistic links between these stressors and endocrine-related diseases, and exploring potential interventions. Key questions to be addressed include how environmental factors predispose individuals to endocrine diseases, the role of hormonal responses in modulating endocrine functions under stress, and the interactions between genetic, environmental, and psychiatric factors in these diseases.To gather further insights into the complex interplay between environmental challenges and endocrine dysregulation, we welcome Original Research and Review articles addressing, but not limited to, the following themes:- Adverse effects of air pollution, climate change, and endocrine-disrupting chemicals on predisposition to endocrine diseases- Hormonal- or transmitter-mediated stress responses to environmental challenges that modulate endocrine and metabolic functions- Mechanistic links or mechanistic basis for environmental stressors, endocrine dysregulation, and cardiometabolic diseases- Interactions between genetic, environmental, and psychiatric factors in endocrine diseases- Interventions, including both traditional and modern medicine, on endocrine-related diseases induced by environmental challenges- The role of endocrine disruption triggered by environmental factors in developmental, reproductive, neurological, cardiovascular, and metabolic disorders.Special Note for Authors:To effectively advance our understanding of environmental challenges and endocrine dysfunction, we highly encourage authors to review the previous Research Topic, ““Environmental Stressors and Metabolic Disease”.