Until now, beyond 100 million chemical compounds have been identified, with the chemical spaces that still expand at an exponential rate. However, all these molecular materials, medicines, and systems still cannot fulfill the requirements of human technology. Although AI applied to chemistry is boosting the molecular space for the synthesis of compounds with different sizes, organic chemical spaces at the nanoscale are still constricted by molecular nanotechnology. It is of the utmost importance to explore the chemical space at the nanoscale ranging from 1 nm to 100 nm for the advancement of future chemistry, materials, medicines, as well as electronics, computing, energy, information, and intelligence technology.
The central challenge is to set up the Molecular Installing and Integrating Technology (MIIT) for advanced molecular platforms, besides molecular engineering, editing, and nanotechnology. Achieving the integration of any molecular building blocks into the ideal molecular ontologies, with diverse formal nanostructures for smart medicines and/or intelligent materials, remains a challenge, although recent advanced C-X editing tools are reported for many areas and structures. Another key problem is to create nanostructures with advanced bottom-up methodologies. The next question is to achieve organic nano-chemistry and bottom-up synthesis with the four precision levels of composition, constitution, configuration, and conformation at the nanoscale. Furthermore, these advances will go towards the installation of molecular nanosystems, such as molecular machines, robots, and molecular circuits as well as molecular reactors.
We welcome the submission of Original Research, Review, Mini Review, and Perspective articles on themes including, but not limited to:
• Organic bottom-up syntheses, such as one-surface chemistry, aromatization, macrocyclization and gridization, two/three-dimensional polymerization, reticular chemistry, DCC
• Diverse covalent nanoscale entities, such as dendrimers, molecular nanocarbon, nanoribbons, nanorings/ nanohoops, nanogrids, 3D cages/MOP/COP, nanopolymers, COF/MOF with well-defined edges
• Other nanostructures, such as carbon nanodots, CNTs, nano-diamonds, molecular machines, nano-enzymes, two-dimensional materials, supramolecular nanoreactor
• High-ordered nano-architectures, such as mechanical interlocking molecules, nano-topology, and so on.
Keywords:
nanosynthesis, Molecular systems, bottom-up synthesis, macrocyclization, gridization, organic nanomaterials
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Until now, beyond 100 million chemical compounds have been identified, with the chemical spaces that still expand at an exponential rate. However, all these molecular materials, medicines, and systems still cannot fulfill the requirements of human technology. Although AI applied to chemistry is boosting the molecular space for the synthesis of compounds with different sizes, organic chemical spaces at the nanoscale are still constricted by molecular nanotechnology. It is of the utmost importance to explore the chemical space at the nanoscale ranging from 1 nm to 100 nm for the advancement of future chemistry, materials, medicines, as well as electronics, computing, energy, information, and intelligence technology.
The central challenge is to set up the Molecular Installing and Integrating Technology (MIIT) for advanced molecular platforms, besides molecular engineering, editing, and nanotechnology. Achieving the integration of any molecular building blocks into the ideal molecular ontologies, with diverse formal nanostructures for smart medicines and/or intelligent materials, remains a challenge, although recent advanced C-X editing tools are reported for many areas and structures. Another key problem is to create nanostructures with advanced bottom-up methodologies. The next question is to achieve organic nano-chemistry and bottom-up synthesis with the four precision levels of composition, constitution, configuration, and conformation at the nanoscale. Furthermore, these advances will go towards the installation of molecular nanosystems, such as molecular machines, robots, and molecular circuits as well as molecular reactors.
We welcome the submission of Original Research, Review, Mini Review, and Perspective articles on themes including, but not limited to:
• Organic bottom-up syntheses, such as one-surface chemistry, aromatization, macrocyclization and gridization, two/three-dimensional polymerization, reticular chemistry, DCC
• Diverse covalent nanoscale entities, such as dendrimers, molecular nanocarbon, nanoribbons, nanorings/ nanohoops, nanogrids, 3D cages/MOP/COP, nanopolymers, COF/MOF with well-defined edges
• Other nanostructures, such as carbon nanodots, CNTs, nano-diamonds, molecular machines, nano-enzymes, two-dimensional materials, supramolecular nanoreactor
• High-ordered nano-architectures, such as mechanical interlocking molecules, nano-topology, and so on.
Keywords:
nanosynthesis, Molecular systems, bottom-up synthesis, macrocyclization, gridization, organic nanomaterials
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.