The intricate interplay between the thyroid and the heart has garnered significant attention due to their essential roles in regulating metabolism and cardiovascular function, respectively. Thyroid hormones profoundly impact cardiac performance, rhythm, and vascular dynamics, while the heart’s pathophysiological conditions can influence thyroid hormone levels. Furthermore, thyroid hormone can influence the response of the heart to stress such as ischemia. This bidirectional relationship highlights the need for comprehensive understanding to optimize patient care.
Recent research has unveiled the molecular mechanisms underlying thyroid hormone-mediated cardiac remodeling, implicating key pathways such as ß-adrenergic signaling and calcium homeostasis. Furthermore, the impact of thyroid dysfunction on cardiovascular diseases, including heart failure and arrhythmias, has been clarified. Recent advances in imaging techniques have paved the way for a non-invasive assessment of thyroid-related cardiac changes, improving early detection and personalized treatment strategies.
This Research Topic also welcomes contributions of any type (clinical trial, correction, editorial, general commentary, hypothesis & theory, methods, mini review, opinion, original research, perspective, policy and practice reviews, review, study protocol, systematic review, technology and code) on the following topics:
- Thyroid Hormones and Cardiac Function
- Thyroid Dysfunction in Heart Diseases
- Molecular Pathways: thyroid hormone receptors, GPCR signaling and epigenetic regulation in cardiac tissues
- Thyroid Imaging and Cardiovascular Assessment
- Therapeutic Implications
The intricate interplay between the thyroid and the heart has garnered significant attention due to their essential roles in regulating metabolism and cardiovascular function, respectively. Thyroid hormones profoundly impact cardiac performance, rhythm, and vascular dynamics, while the heart’s pathophysiological conditions can influence thyroid hormone levels. Furthermore, thyroid hormone can influence the response of the heart to stress such as ischemia. This bidirectional relationship highlights the need for comprehensive understanding to optimize patient care.
Recent research has unveiled the molecular mechanisms underlying thyroid hormone-mediated cardiac remodeling, implicating key pathways such as ß-adrenergic signaling and calcium homeostasis. Furthermore, the impact of thyroid dysfunction on cardiovascular diseases, including heart failure and arrhythmias, has been clarified. Recent advances in imaging techniques have paved the way for a non-invasive assessment of thyroid-related cardiac changes, improving early detection and personalized treatment strategies.
This Research Topic also welcomes contributions of any type (clinical trial, correction, editorial, general commentary, hypothesis & theory, methods, mini review, opinion, original research, perspective, policy and practice reviews, review, study protocol, systematic review, technology and code) on the following topics:
- Thyroid Hormones and Cardiac Function
- Thyroid Dysfunction in Heart Diseases
- Molecular Pathways: thyroid hormone receptors, GPCR signaling and epigenetic regulation in cardiac tissues
- Thyroid Imaging and Cardiovascular Assessment
- Therapeutic Implications
