Research Topic

RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications

About this Research Topic

This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications.

In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional ...

This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications.

In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.

This Research Topic aims at gathering manuscripts addressing diseases caused by defects in RNA metabolism. We particularly welcome studies:
- linking the basic science – i.e. elucidating the molecular mechanisms of RNA regulation – and the implications and applications for therapeutic approaches
- focusing on the potential role of non-coding RNAs in diagnosis and therapy of RNA diseases

We welcome the following article types: Original Research, Reviews, Mini-Reviews, Perspectives, Opinions, and Methods.


Keywords: RNA splicing, RNA modification, RNA processing, translation, RNA transport


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

31 January 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

31 January 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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