RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications

134.3K

views

69

authors

12

articles

RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications

134.3K

views

69

authors

12

articles

Editorial

16 July 2019

Editorial: RNA Diseases in Humans—From Fundamental Research to Therapeutic Applications

Naoyuki Kataoka

,

Akila Mayeda

and

Kinji Ohno

4,135 views

3 citations

Editors

3

Naoyuki Kataoka

The University of Tokyo

Nagoya University

Fujita Health University

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About

This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications.

In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.

This Research Topic aims at gathering manuscripts addressing diseases caused by defects in RNA metabolism. We particularly welcome studies:
- linking the basic science – i.e. elucidating the molecular mechanisms of RNA regulation – and the implications and applications for therapeutic approaches
- focusing on the potential role of non-coding RNAs in diagnosis and therapy of RNA diseases

We welcome the following article types: Original Research, Reviews, Mini-Reviews, Perspectives, Opinions, and Methods.

This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications.

In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.

This Research Topic aims at gathering manuscripts addressing diseases caused by defects in RNA metabolism. We particularly welcome studies:
- linking the basic science – i.e. elucidating the molecular mechanisms of RNA regulation – and the implications and applications for therapeutic approaches
- focusing on the potential role of non-coding RNAs in diagnosis and therapy of RNA diseases

We welcome the following article types: Original Research, Reviews, Mini-Reviews, Perspectives, Opinions, and Methods.

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Editors

Naoyuki Kataoka

The University of Tokyo

Nagoya University

Fujita Health University

Impact

134,261 Total views

96,534 Article views

28,573 Article downloads

9,154 Topic views

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Frontiers in Molecular Biosciences

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Frontiers in Genetics

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