Inflammatory and autoimmune diseases are diseases of serious threat to human health and life. Over the past few decades, great effort has been made to understand the molecular mechanisms of inflammatory and autoimmune diseases, which has led to the development of drug discovery.
Natural products, especially monomer compounds, possess structural diversity and significant biological activity, which are important sources of drugs and lead compounds, playing an important role in innovative drug development. In the past few years, scientists have made many exciting achievements in chemistry, pharmaceutical resources, pharmacology, preparations, new drug development, and other related fields. One of the successful examples is Prof. Tu You-You, who won the 2015 Nobel Prize in Physiology or Medicine for her research on a natural compound artemisinin. A plethora of studies have demonstrated that artemisinin and its analogs exhibited anti-parasitic, anti-tumor, and anti-inflammatory activities and showed potent effects in the treatment of immune diseases. Therefore, natural products have great development prospects in the field of inflammatory and autoimmune diseases. Research focusing on the functional implications of natural products and their derivatives for the treatment of inflammatory and autoimmune diseases will promote the discovery of new drugs with independent intellectual property rights.
Recently, early diagnosis and treatment have largely ameliorated the management and long-term prognosis of inflammatory and autoimmune diseases. Nevertheless, prolonged therapy of drugs constantly results in resistance and side effects. Therefore, it is necessary to develop novel drugs for alleviating treatment failure in inflammatory and autoimmune diseases.
This Research Topic focuses on seeking natural products and their derivatives to treat inflammatory and autoimmune diseases. In addition, we look forward to screening biomarkers of inflammatory and autoimmune diseases based on network pharmacology or genetic sequencing and finding new targeted drugs for the treatment of inflammatory and autoimmune diseases.
We welcome researchers to submit Perspectives, Original Research articles, Reviews, Comments, and Letters, including but not limited to the following subtopics:
(1) Effect of natural products and their derivatives in treating inflammatory diseases.
(2) Effect of natural products and their derivatives in treating autoimmune diseases.
(3) Inhibitors of proteins related to inflammatory diseases.
(4) Inhibitors of proteins related to autoimmune diseases.
(5) Network pharmacology and inflammatory diseases.
(6) Network pharmacology and autoimmune diseases.
Please NOTE: Bioinformatics analysis without experimental validation is not considered.
Inflammatory and autoimmune diseases are diseases of serious threat to human health and life. Over the past few decades, great effort has been made to understand the molecular mechanisms of inflammatory and autoimmune diseases, which has led to the development of drug discovery.
Natural products, especially monomer compounds, possess structural diversity and significant biological activity, which are important sources of drugs and lead compounds, playing an important role in innovative drug development. In the past few years, scientists have made many exciting achievements in chemistry, pharmaceutical resources, pharmacology, preparations, new drug development, and other related fields. One of the successful examples is Prof. Tu You-You, who won the 2015 Nobel Prize in Physiology or Medicine for her research on a natural compound artemisinin. A plethora of studies have demonstrated that artemisinin and its analogs exhibited anti-parasitic, anti-tumor, and anti-inflammatory activities and showed potent effects in the treatment of immune diseases. Therefore, natural products have great development prospects in the field of inflammatory and autoimmune diseases. Research focusing on the functional implications of natural products and their derivatives for the treatment of inflammatory and autoimmune diseases will promote the discovery of new drugs with independent intellectual property rights.
Recently, early diagnosis and treatment have largely ameliorated the management and long-term prognosis of inflammatory and autoimmune diseases. Nevertheless, prolonged therapy of drugs constantly results in resistance and side effects. Therefore, it is necessary to develop novel drugs for alleviating treatment failure in inflammatory and autoimmune diseases.
This Research Topic focuses on seeking natural products and their derivatives to treat inflammatory and autoimmune diseases. In addition, we look forward to screening biomarkers of inflammatory and autoimmune diseases based on network pharmacology or genetic sequencing and finding new targeted drugs for the treatment of inflammatory and autoimmune diseases.
We welcome researchers to submit Perspectives, Original Research articles, Reviews, Comments, and Letters, including but not limited to the following subtopics:
(1) Effect of natural products and their derivatives in treating inflammatory diseases.
(2) Effect of natural products and their derivatives in treating autoimmune diseases.
(3) Inhibitors of proteins related to inflammatory diseases.
(4) Inhibitors of proteins related to autoimmune diseases.
(5) Network pharmacology and inflammatory diseases.
(6) Network pharmacology and autoimmune diseases.
Please NOTE: Bioinformatics analysis without experimental validation is not considered.