About this Research Topic
Regenerative neurorehabilitation encompasses a variety of approaches, including cellular transplants, use of biocompatible materials and implants, the mobilization of endogenous neural stem cells, gene therapy, and the application of neurotrophic factors or drugs that promote healing. In particular, gene and cell therapy are assuming a pivotal importance since these techniques offer unprecedented opportunities to precisely target and modify the genetic and cellular components crucial for neuroregeneration.
The field of stem cell therapy in neurological conditions is rapidly evolving, and new findings are leading to the production of genetic modifications to human stem cell lines that allow the transplanted cells to be tracked within the CNS. This approach is showing promising potential and seeks to overcome the limitations of conventional rehabilitation methods.
Notably, the integration of regenerative medicine with the principles of rehabilitation can introduce new dimensions to patient care. Addressing the body's inherent inability to naturally heal or regenerate neuronal circuits, this approach seeks to invigorate self-repair mechanisms and drive these circuits versus a functional recovery. This approach can lead to patients regaining physical or cognitive abilities more effectively and rapidly.
Regenerative neurorehabilitation could span a spectrum, encompassing spinal cord injuries, traumatic brain injuries, strokes, and neurodegenerative disorders like Parkinson's and Alzheimer's diseases. These interventions should be carefully timed and tailored to each patient’s unique circumstance and needs, thus adding a substantial level of personalization to the process.
Regenerative neurorehabilitation is an exhilarating frontier in neurology, promising to redefine how we manage and treat a spectrum of neurological conditions. As we continue to understand the depths of the human brain and the nervous system, the hope is that regenerative neurorehabilitation, with its emphasis on gene and cell therapy, might be the key to unlocking neural recovery unlike ever before.
This Research Topic welcomes any types of manuscripts supported by Frontiers in Neurology, pertaining but not limited to the following themes:
• Stem Cells Therapy
• Gene Therapy
• Functional recovery
• Neural regeneration
• Regenerative medicine
• Neurorehabilitation
Keywords: Regenerative medicine, Stem Cells, Neural regeneration, Functional recovery, Integrative therapies, Gene Therapy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.