About this Research Topic
The purpose of this Research Topic is to give a complete assessment of current information about the influence of environmental variables on neurodevelopmental disorders. The increasing frequency of these disorders, as well as the huge burden on affected individuals, their families, and society as a whole, warrants additional research into etiologic and risk factors. We hope to highlight the relevance of addressing environmental effects in the diagnosis, prevention, and intervention options for individuals with neurodevelopmental disorders by reviewing existing studies, and spreading original research using animal models of these disorders.
We welcome diverse background researchers to contribute to this research topic. Original research papers, reviews, viewpoints, and case studies, may be included in manuscripts. Topics of potential relevance include, but are not limited to:
• Identification of environmental risk factors through investigations of prenatal exposure to chemicals, maternal stress, air pollution, dietary factors, etc.
• Interactions between genes and environment including investigation on epigenetic mechanisms, gene-environment interactions.
• Uncovering the mechanisms through which environmental factors affect neurodevelopment by using animal models such as mouse and zebrafish.
• Reviews and meta-analyses that summarize existing knowledge about gene-environment interactions in neurodevelopmental disorders.
• Neuroimaging studies to investigate the neural correlates of environmental impacts on neurodevelopment.
Please note: If patient data are analyzed, a comprehensive description of the patients including sex, age, diagnostic criteria, inclusion and exclusion criteria, disease stage, therapy received, comorbidities as well as additional clinical information and assessment of clinical response/effects should be included. If genetic, proteomics, metabolomics, or other omics data are analyzed, a comprehensive description of the methods and the rationale for the selection of the specific data studied should be provided. Studies solely based on the analysis of public databases or published evidence, with no further experimental insights or experimental validation, will not be included in this Research Topic.
All the manuscripts submitted to the collection will need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here). Please self-assess your MS using the ConPhyMP tool, and follow the standards established in the ConPhyMP statement Front. Pharmacol. 13:953205. Please note the traditional context including the primary background and modern uses with supporting references must be included in the manuscript introduction.
If your MS involves plant or fungal extracts, check your MS using this tool.
Keywords: Neurodevelopmental disorders, mouse, zebrafish, environmental factors, epigenetics
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.