About this Research Topic
Pioneering work in 2008 first applied SRM mass spectrometry to quantify protein abundance in Arabidopsis and Medicago and since then a large number of other SRM assays have been developed for proteins in a wide variety of species. The impact this approach has had on plant science is undeniable and it was awarded the 2012 Nature Methods “Method of the Year”. However, the ability to quantify all proteins in all species by SRM mass spectrometry in plants has yet to be realized. To achieve this, researchers in the field need to come together to collate their individual peptide or SRM assays and share these with the wider research community.
In recent years targeted proteomics has diversified somewhat to include approaches comparable to SRM. Parallel reaction monitoring (PRM) wherein all precursor transitions are monitored in parallel has been accepted particularly on a QqOrbi MS and has found application in plants. The targeted extraction of precursor transitions from data-independent acquisition (DIA) once-and-forever datasets is another innovative example that holds promise.
This Research Topic provides an opportunity to bring together the current advances in plant targeted mass spectrometry of peptides/proteins with research tools and databases that have been developed to enable the plant science researchers to embrace this highly effective method of protein quantitation.
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