Microfluidic-based technologies have attracted significant research attention and have become increasingly popular in applications for bio-related detection and analytical chemistry. The integration of microfluidics with various detection modalities has revolutionized the field of chemical and biochemical analysis, offering unique advantages such as reduced sample volume, improved sensitivity, and enhanced control over fluid handling. The development of microfluidic technology encompasses various aspects, including sample manipulation techniques for DNA extraction, pathogen isolation, and exosome enrichment, as well as particle manipulation techniques for precise control. It also includes integrated analysis and detection technologies for biomarker detection and quantitative analysis of chemical molecules. Furthermore, microfluidic technology has been utilized in the synthesis of nanomaterials and micro-mixing techniques for efficient reagent reactions.

This call for participation invites contributions to a research topic focusing on the latest advancements, strategies, and emerging trends in microfluidic chips for analytical and biological applications. The novelty of these studies is highlighted through the creation of miniaturized devices tailored for various applications such as food safety, environmental monitoring, and water quality assessment. The progress encompasses: (1) advanced microfluidic sample manipulation techniques, including droplet generation, particle manipulation, immunomagnetic separation, and magnetophoresis, which enable precise control and manipulation of samples;(2) advanced microfluidic integrated detection techniques, such as integrated immunodetection and integrated nucleic acid detection, which enhance the sensitivity and efficiency of chemical and biological analysis; (3) the applications of microfluidics in on-site, real-time detection and healthcare screening.

Key topics of interest include but are not limited to:

1. Microfluidic chip designs for efficient droplet generation, manipulation, and analysis
2. Novel microfluidic platforms or POCT devices for biosensing applications
3. Integration of microfluidic systems with sample preparation techniques
4. Advances in microfluidic-based cell manipulation and analysis
5. Advanced microfluidic micromixers
6. Microfluidic approaches for high-throughput screening and drug discovery

Are you interested in contributing a manuscript to this Research Topic?

Advanced Microfluidic Chips for Analytical and Biological Applications