About this Research Topic
This research topic aims to assemble a collection of state-of-the-art research articles that bring novel insights into the mechanisms contributing to the development of drug resistance. Specifically, we seek to understand the genetic, environmental, and evolutionary factors that drive resistance in infectious microbes. By identifying new drugs and drug targets, we hope to develop strategies that can effectively combat resistance and improve the efficacy of current treatments. The primary objective is to answer key questions about the mechanisms of resistance and to test hypotheses related to the development and spread of drug-resistant strains.
To gather further insights into the upsurge of resistance in infectious microbes, we welcome articles addressing, but not limited to, the following themes:
- Exploring the role of genes and their mutations in the development of resistance.
- Insight into the role of biofilm formation in the development of resistance.
- Novel insights into the role of immune evasion in the development of resistance.
- Identification of novel druggable targets and drug molecules.
- Role of membrane proteins or transporters in drug resistance.
- Impact of drug resistance on host-pathogen interactions.
- Updates on the mechanisms of antibiotic action and resistance.
- Effect of environment and nutrients on the emergence of drug resistance.
- Epidemiological studies addressing concerns over increased drug resistance.
Keywords: Drug resistance, Infectious diseases, Malaria, Tuberculosis, Plasmodium, Mycobacterium, drug, targets, Antimicrobial, Antibiotics
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.