Synthetic Biology has rapidly evolved into a pioneering "science of synthesis," revolutionizing how we design and engineer life. While these advancements hold immense promise, they also raise profound societal and ethical questions that demand urgent interdisciplinary dialogue and clearer public communication.

The field’s fluidity, rapid progress, and uncertain environmental impacts present unique challenges. Key concerns include the manipulation of organisms, the introduction of synthetic life, and the need for adaptable political and regulatory frameworks. Addressing these issues requires not only technical innovation but also thoughtful ethical and societal reflection.

This Research Topic, "Navigating the Frontier: Ethical Considerations, Policies, and Societal Impacts of Synthetic Biology," delves into these complex dimensions. It explores how Synthetic Biology reshapes ethical, philosophical, and societal norms while driving breakthroughs in medicine, materials, and beyond. By bridging engineering and biology, the field fosters collaborations that illuminate the intricate relationship between technology and society.

Synthetic Biology is a cutting-edge "technoscience" that blends biology, engineering, and design, sparking deep philosophical questions about its novelty and contributions to knowledge. Tools like CRISPR have revolutionized our ability to edit life, raising important ethical questions that demand ongoing scrutiny.

Recent breakthroughs in genome editing and the creation of synthetic life forms are challenging long-held biological theories. These advancements offer unprecedented opportunities to reshape both nature and humanity. However, the rapid pace of progress calls for continuous updates, critical evaluation, and innovative approaches to responsibly address emerging risks, ethical challenges, and societal impacts.

Therefore, we invite opinion, perspective and review articles exploring the following themes:

· Reflection of Synthetic Biology from philosophical perspectives, addressing ethical and societal issues, and proposing governance measures.

· Ethical and Social Concerns in Synthetic Biology: The ethical implications of engineering that blurs the boundaries between life and non-life, including questions of epistemological and ontological novelty, as well as potential environmental impacts.

· Exploration of ethical considerations, such as the moral implications of creating life and the societal impact of biotechnological advancements.

*We expect all manuscript abstracts to be submitted and approved by the Topic Editors in advance, ensuring a high standard of quality and relevance*

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Navigating the Frontier: Ethical Considerations, Policies, and Societal Impacts of Synthetic Biology